Also efficacy of monotherapy versus combinations • Indications: … • Detailed understanding of the mechanism of action for each drug/drug class. DRUG INTERACTIONS STENDRA can potentiate the hypotensive effect of nitrates, alpha-blockers, antihypertensives, and alcohol (7.1) CYP3A4 inhibitors (e.g., ketoconazole, ritonavir, erythromycin) increase STENDRA exposure (7.2) USE IN SPECIFIC POPULATIONS Do not use in patients with severe renal impairment (8.6) Do not use in patients with severe hepatic impairment (8.7) See 17 for PATIENT … These are the drugs which antagonize the pharmacological action of sympathomimetic agents or alter the function of sympathetic nervous system inside the body. 1811 0 obj <>stream
Anti Hypertensive Drugs By: Dr. Ali Osman Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. 14 0 obj<> endobj Classification: ADVERTISEMENTS: On the basis of mechanism of action. Rauwolfia serpentina is used … 0000013005 00000 n 0000003695 00000 n Diuretics. - Pancreatic and/or extra-pancreatic mechanism(s)? V���Zo� I��@ڋ���Č��8�G ����H3�Z� 2�sh 1. 0000023138 00000 n Sympathetic Inhibitors 2. 0000007453 00000 n 0000015422 00000 n 0000011202 00000 n h�b```��,�����(���1�q` $�0�00� pharmacological classification of drugs first edition 732 tariq ahmad | tareeqahmad@hotmail.com department of pharmacy, university of lahore 14 • nicardipine • nifedipine (adalat) • nisoldipine 4) α-adreno receptor blockers • doxazosin (doxcil) • prazosin (minipres) • terazosin (hytrin) 5) •centrally acting adrenergic drugs clonidine (generic, catapres) • α-methyl dopa 6) •vasodilators hydralazine (generic, … Central and Peripheral Inhibitors: i. Rauwolfia Group of Drugs: ADVERTISEMENTS: These are useful in mild to moderate hypertension. However, the difficulties encountered in the conception, development, costs, and delivery to the market of new classes of antihypertensive agents highlights the hurdles that must … 14 29
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The development of new antihypertensive drugs acting on new targets, with different modes of action, therefore, remains essential, to improve blood pressure control and reduce the residual burden of cardiovascular risks further. 0000009310 00000 n After reading this article we will learn about the classification of antiadrenergic drugs . - Insulin dependent or independent action - Compare drugs from different structural classes in terms of mechanism • Relative potency and efficacy within a structural series (sulfonylureas) and across series. 0000001107 00000 n
%PDF-1.3 %���� Interactions between antihypertensive and other drugs Drugs (class) Interaction with Mechanism Effect β-Blockers verapamil diltiazem Additive effects A-V conduction impaired; risk of A-V block oral antidiabetics β2-receptor blockade symptoms of hypoglycaemia are suppressed broncho-spasmolytic agents β2-receptor blockade suppression of the bronchospasmolytic effect dobutamine β1-receptor … 0 Vasodilators 3. trailer 0000020888 00000 n Microsoft Word - Q24 Classify antihypertensive agents by their mechanism of action, with a brief outline of each mechanism, and an example of a drug in each class (Sept 2010).docx Created Date: 1/6/2015 4:46:06 AM Orally Given Diuretics Of the various groups of antihypertensive drugs, the diuretics for oral administration have the greatest overall clinical usefulness. 0000021026 00000 n Antihypertensive drugs fall into the following four major categories according to their site of action, but there is considerable overlap: 1.
The purpose of this communication is to review mechanisms of action and hemodynamic effects of the commonly employed antihypertensive drugs. 0000005555 00000 n 0000015799 00000 n 0000015850 00000 n 0000013349 00000 n If you continue browsing the site, you agree to the use of cookies on this website. 0000012754 00000 n 0000011635 00000 n 0000046322 00000 n tZ̦��h�Y���꧒c�.p�{���:�!��;��8�Z'��3��y�3A@�w���;O2���� ���¿k6�1n�s=�%�L� �!^��C�v�Hf�� � �L�� � d��5g�O%@��Mp�3�3��}a{#���,���m����\``m��� endstream endobj startxref endstream endobj 1790 0 obj < 0000078618 00000 n %%EOF 1802 0 obj <>/Filter/FlateDecode/ID[<0DBE0BC81142B24385201B592EB77B63><280899BC0382A147B1970FE1C452231E>]/Index[1789 23]/Info 1788 0 R/Length 72/Prev 391464/Root 1790 0 R/Size 1812/Type/XRef/W[1 2 1]>>stream 1. α-Adrenoceptor Antagonists: Phenoxy-benzamine: (i) Phenoxy-benzamine is a … 0000016153 00000 n 0000000016 00000 n xref 0000000876 00000 n Captopril 4. < 0000018813 00000 n
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