Changes in glycemic control may occur in such patients, with either hyperglycemia or hypoglycemia possible. The risk of lactic acidosis increases with the degree of renal dysfunction and the patient's age. Treatment options include medications, a type 2 diabetes diet, and other lifestyle changes.Diabetes and eye problems are generally caused by high blood sugar levels over an extended period of time. Glipizide and metformin is used together with diet and exercise to improve blood sugar control in adults with Glipizide and metformin may also be used for purposes not listed in this medication guide.You should not use glipizide and metformin if you have severe kidney disease or If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking glipizide and metformin.You should not use glipizide and metformin if you are allergic to glipizide or metformin, or if you have:If you need to have any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking glipizide and metformin.a genetic enzyme deficiency called glucose-6-phosphate dehydrogenase (G6PD) deficiency;if you are over 80 years old and have not recently had your kidney function checked.Follow your doctor's instructions about using this medicine Metformin may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy.
Learn to avoid these diet blunders and watch the...See pictures of celebrities that have been diagnosed with type 1 or type 2 diabetes including Mary Tyler Moore, Salma Hayek, and...Learn 10 simple ways to better manage your diabetes.
The therapeutic goal in all patients with type 2 diabetes is to decrease FPG, PPG, and HbA1c to normal or as near normal as possible. Side effects include high blood pressure, muscle or joint pain, upper respiratory tract infection, urinary tract infection, vomiting, stomach pain, decreased appetite, metallic taste in the mouth.Learn about type 2 diabetes warning signs, symptoms, diagnosis, and treatment options. Thereafter, HbA1c should be measured at intervals of approximately 3 months to assess the effectiveness of therapy. Glipizide and metformin hydrochloride tablets should be given with meals and should be initiated at a low dose, with gradual dose escalation as described below, in order to avoid hypoglycemia (largely due to glipizide), reduce GI side effects (largely due to metformin), and permit determination of the minimum effective dose for adequate control of blood glucose for the individual patient.With initial treatment and during dose titration, appropriate blood glucose monitoring should be used to determine the therapeutic response to glipizide and metformin hydrochloride tablets and to identify the minimum effective dose for the patient. Glipizide and metformin hydrochloride tablets should be withdrawn until the situation is clarified. Generally, elderly, debilitated, and malnourished patients should not be titrated to the maximum dose of glipizide and metformin hydrochloride tablets USP to avoid the risk of hypoglycemia.
For patients whose FPG is 280 mg/dL to 320 mg/dL a starting dose of glipizide and metformin hydrochloride tablets USP, 2.5 mg/500 mg twice daily should be considered. It lowers blood sugar and may increase your risk of Stop using glipizide and metformin and call your doctor at once if you have:heart problems-- swelling, rapid weight gain, feeling short of breath;severe hypoglycemia--extreme weakness, blurred vision, sweating, trouble speaking, tremors, stomach pain, confusion, seizure; orlactic acidosis--unusual muscle pain, trouble breathing, stomach pain, vomiting, irregular heart rate, dizziness, feeling cold, or feeling very weak or tired.This is not a complete list of side effects and others may occur.
The daily dose should be titrated in increments of no more than 5 mg/500 mg up to the minimum effective dose to achieve adequate control of blood glucose or to a maximum dose of 20 mg/2000 mg per day.Glipizide/metformin HCl tablet is not recommended for use during pregnancy or for use in pediatric patients. The initial and maintenance dosing of glipizide and metformin hydrochloride tablets USP should be conservative in patients with advanced age, due to the potential for decreased renal function in this population. The decision to switch to the nearest equivalent dose or to titrate should be based on clinical judgment. In order to avoid hypoglycemia, the starting dose of glipizide and metformin hydrochloride tablets USP should not exceed the daily doses of glipizide or metformin already being taken. The two types of diabetes are referred to as type 1 (insulin dependent) and type 2 (non-insulin dependent).
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