40 kg, 0.1 mg/kg IV >40 kg, 4 mg IV >12 years 2002
The 4-mg dose is taken again 4 and 8 hours after the first dose. 2026938-overview
Drugs
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Cada vez más publicaciones recomiendan incorporar ondansetrón en el manejo de las gastroenteritis agudas (GEA) en Urgencias de Pediatría (UP) 1–5.Dado que no hay referencias al respecto de centros nacionales, queremos describir la experiencia en nuestro Servicio de UP.
Follow your doctor's orders or the directions on the label.
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per dose 8 mg), dose to be administered immediately before chemotherapy, then 150 micrograms/kg every 4 hours (max.
Right Sided Cerebellar Ataxia with Occipital Encephalocele (Arnold -Chiari Type III Malformation)
Portions of this document last updated: Sept. 01, 2020Copyright © 2020 IBM Watson Health.
0.15 mg/kg (150 mcg/kg) IV infused over 15 minutes beginning 30 minutes prior to the initiation of emetogenic chemotherapy. Ask a Doctor
All children received three 0.15 mg/kg doses of intravenous ondansetron, administered 30 minutes before the start of chemotherapy and then at 4 and 8 hours after the first dose.
Diseases & Conditions
If you log out, you will be required to enter your username and password the next time you visit. Store at room temperature, away from heat and direct light. We comply with the HONcode standard for trustworthy health information - Do not double doses.If you miss a dose of this medicine, and you feel nauseated or you vomit, take the missed dose as soon as possible.Keep the medicine in the foil pouch until you are ready to use it.
≥6 months: 0.15 mg/kg over 15 min administered 30 min before chemotherapy, then repeated 4 and 8 hr after first dose; not to exceed 16 mg/dose (32 mg no longer recommended because of increased risk of QT prolongation) Postoperative Nausea & Vomiting. Controlled studies in pregnant women show no evidence of fetal risk.Mechanism not fully characterized; selective 5-HT3 receptor antagonist; binds to 5-HT3 receptors both in periphery and in CNS, with primary effects in GI tractHas no effect on dopamine receptors and therefore does not cause extrapyramidal symptomsBioavailability: 56-71% (PO); food increases extent of absorption (17%)Peak plasma time: IV, end of infusion; IM, 30 min; PO, 2 hr (tablet) or 1 hr (soluble film)Extensive hepatic metabolism, with hydroxylation followed by glucuronide (indole ring) or sulfate conjugation; metabolized by CYP2D6 and partly by CYP1A2 and CYP3A4Metabolites: Glucuronide conjugate, sulfate conjugate (inactive)Half-life: 2-7 hr (children <15 years); 3-7 hr (adults); patients with mild to moderate hepatic impairment, 12 hr; patients with severe hepatic impairment (Child-Pugh class C), 20 hrY-site: Acyclovir, allopurinol, aminophylline, amphotericin B, amphotericin B cholesteryl sulfate, ampicillin, ampicillin/sulbactam, amsacrine, cefepime, cefoperazone, 5-fluorouracil (5-FU; at 1 mg/mL ondansetron and 16 mg/mL 5-FU; may be compatible at 0.8 mg/mL 5-FU and up to 160 mcg/mL ondansetron), furosemide, ganciclovir, lorazepam, meropenem (at 50 mg/mL meropenem and 1 mg/mL ondansetron; may be compatible at 1 mg/mL each), methylprednisolone, piperacillin, sargramostim, sodium bicarbonateAdditive (partial list): Cisplatin, cyclophosphamide, cytarabine, decarbazine, dacarbazine with doxorubicin(? This was followed by the administration of ondansetron hydrochloride tablets ranging from 4 to 24 mg daily for 3 days.
Contact the applicable plan If your dose is different, do not change it unless your doctor tells you to do so.The amount of medicine that you take depends on the strength of the medicine.
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