Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Side effects not requiring immediate medical attention. Some side effects of clopidogrel may occur that usually do not need medical attention.
Nearly every medical intervention has both good effects and some unwanted side effects… QUESTION In the U.S., 1 in every 4 …
Call your doctor for medical advice about side effects. Ask your doctor to learn more. Other bleeding events that were reported more frequently in the clopidogrel group were epistaxis, hematuria, and bruise.The overall incidence of bleeding is described in Table 1.In COMMIT, similar rates of major bleeding were observed in the Plavix and placebo groups, both of which also received aspirin (see Table 2).In CAPRIE, gastrointestinal hemorrhage occurred at a rate of 2.0% in those taking Plavix versus 2.7% in those taking aspirin; bleeding requiring hospitalization occurred in 0.7% and 1.1%, respectively. The incidence of intracranial hemorrhage was 0.4% for Plavix compared to 0.5% for aspirin.Other bleeding events that were reported more frequently in the Plavix group were epistaxis and hematoma.In CURE and CHARISMA, which compared Plavix plus aspirin to aspirin alone, there was no difference in the rate of adverse events (other than bleeding) between Plavix and placebo.In CAPRIE, which compared Plavix to aspirin, pruritus was more frequently reported in those taking Plavix. These side effects may go away during treatment as your body adjusts to the medicine. Some side effects of clopidogrel may occur that usually do not need medical attention. Available for Android and iOS devices.We comply with the HONcode standard for trustworthy health information - These side effects may go away during treatment as your body adjusts to the medicine. O 03.
You may report them to the The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Our Plavix Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. Call your doctor for medical advice about side effects. The clinically important adverse reactions observed in trials comparing Plavix plus aspirin to placebo plus aspirin and trials comparing Plavix alone to aspirin alone are discussed below.In CURE, Plavix use with aspirin was associated with an increase in major bleeding (primarily gastrointestinal and at puncture sites) compared to placebo with aspirin (see Table 1). In the U.S., 1 in every 4 deaths is caused by heart disease. Tests are available to identify patients who are CYP2C19 poor metabolizers. Bristol-Myers Squibb, Princeton, NJ. Call your doctor for medical advice about side effects. Bleeding requiring hospitalization occurred in 0.7% clopidogrel-treated and 1.1% aspirin-treated patients.In CAPRIE (n=19,185), 4.2% of patients receiving clopidogrel developed a rash compared to 3.5% in the aspirin group. The effectiveness of clopidogrel hydrogen sulfate results from its antiplatelet activity, which is dependent on its conversion to an active metabolite by the cytochrome P450 (CYP) system, principally CYP2C19. Good & Bad Side Effects. Consider use of another platelet P2Y12 inhibitor in patients identified as CYP2C19 poor metabolizers..Along with its needed effects, clopidogrel (the active ingredient contained in Some side effects of clopidogrel may occur that usually Check with your health care professional if any of the following side effects The most commonly reported adverse effect was bleeding, including life threatening and fatal bleeding.In the COMMIT study (n=45,852), the incidence of major non-cerebral or cerebral bleeding was 0.6% in clopidogrel plus In the CURE study (n=12,562), the incidence of fatal bleeding (0.2%) and In the CAPRIE study (n=19,185), gastrointestinal hemorrhage occurred in 2% of patients taking clopidogrel compared to 2.7% taking aspirin. You may report side effects to FDA at 1-800-FDA-1088.
Side effects not requiring immediate medical attention. For acute coronary syndrome with a non-ST elevation MI, the initial recommended dose is 300 mg, followed by a 75 mg dose per day; for ST elevation MIs, the initial and continuing dose is 75 mg per day. This is not a complete list of side effects and others may occur. Portions of this document last updated: June 01, 2020 No other difference in the rate of adverse events (other than bleeding) was reported.The following adverse reactions have been identified during postapproval use of Plavix. Other side effects not listed may also occur in some patients.
Plavix Side Effects by Likelihood and Severity COMMON side effects.
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