Myocardial oxygen consumption or demand (as measured by the pressure-rate product, tension-time index, and stroke-work index) is decreased and a more favorable supply-demand ratio can be achieved. Nevertheless, there was no evidence of mutagenicity in an In a 3-generation reproduction study, rats received dietary nitroglycerin at doses up to about 434 mg/kg/day for 6 months prior to mating of the F0 generation, with treatment continuing through successive F1 and F2 generations. Clearance (13.6 L/min) greatly exceeds hepatic blood flow. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. Storage Keep Sublingual Viagra in its original container. Follow all instructions closely. Hypotension induced by nitroglycerin may be accompanied by paradoxical bradycardia and increased angina pectoris. Do not chew or swallow it. Skip the missed dose if your next dose is less than 2 hours away. PDE-5-Inhibitors such as avanafil, sildenafil, vardenafil, and tadalafil have been shown to potentiate the hypotensive effects of organic nitrates.Nitroglycerin sublingual tablets are contraindicated in patients who are taking soluble guanylate cyclase (sGC) stimulators. Only the smallest dose required for effective relief of the acute angina attack should be used. Interactions between your selected drugs and food Moderate sildenafil food Applies to: Viagra (sildenafil) If you are receiving therapy with sildenafil you should avoid the regular consumption of large amounts of grapefruits and grapefruit juice. Administer nitroglycerin sublingual tablets at rest, preferably in the sitting position.Nitroglycerin Sublingual Tablets, USP are supplied as white to off-white, round, flat-faced tablets in three strengths: Do not use nitroglycerin sublingual tablets in patients who are taking PDE-5 Inhibitors, such as avanafil, sildenafil, tadalafil, vardenafil hydrochloride. The 1,2- and 1,3-dinitroglycerin metabolites have been reported to possess approximately 2% and 10%, respectively, of the pharmacological activity of nitroglycerin. This includes prescription and over-the-counter medicines, Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Nitrostat only for the indication prescribed.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Copyright 1996-2020 Cerner Multum, Inc.
VIAGRA is formulated as blue, film-coated rounded-diamond-shaped tablets equivalent to 25 mg, 50 mg and 100 mg of sildenafil for oral administration. Apotheke Deutschland für sie.
The high dose was associated with decreased feed intake and body weight gain in both sexes at all matings. Use Sublingual Viagra as directed by your doctor. Do not use more than 3 tablets in 15 minutes.Seek emergency medical attention if your chest pain gets worse or lasts more than 5 minutes, especially if you have trouble breathing or feel weak, dizzy, or nauseated, or lightheaded.You may feel a slight burning or stinging in your mouth when you use this medicine. You could have more side effects. Tell your doctor if you are concerned about any side effects you experience. We comply with the HONcode standard for trustworthy health information - (See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling.Nitroglycerin sublingual tablets are indicated for the acute relief of an attack or acute prophylaxis of angina pectoris due to coronary artery disease.Administer one tablet under the tongue or in the buccal pouch at the first sign of an acute anginal attack.
Read all information given to you. Call your doctor for medical A decrease in therapeutic effect of sublingual nitroglycerin may result from use of long-acting nitrates.Severe hypotension, particularly with upright posture, may occur with small doses of nitroglycerin particularly in patients with constrictive pericarditis, aortic or mitral stenosis, patients who may be volume-depleted, or are already hypotensive. Higher plasma concentrations of the dinitro metabolites, along with their nearly 10-fold longer elimination half-lives, may contribute significantly to the duration of pharmacologic effect. The elimination half-life of 1,2- and 1,3-dinitroglycerin is 36 and 32 minutes, respectively. You may report side effects to FDA at 1-800-FDA-1088.Many drugs can interact with nitroglycerin. Nitrostat can relieve this pain.You should not use Nitrostat if you are also using medicine to treat You should not use Nitrostat if you are allergic to nitroglycerin, or if you are using medicine to treat pulmonary arterial hypertension (PAH), such as You should not use Nitrostat sublingual tablets if you have:symptoms of circulation problems or shock (pale skin, cold sweat, fast or irregular heartbeats, sudden weakness or feeling like you might pass out); orTo make sure Nitrostat is safe for you, tell your doctor if you have ever had:It is not known whether Nitrostat will harm an unborn baby.
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