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Published animal studies show that rat offspring exhibit alterations in behavior and brain development including decreased cellular proliferation and differentiation when dams were treated subcutaneously with Terbutaline during the late stage of pregnancy and lactation period. 1.
In the mother, these adverse reactions include increased heart rate, transient hyperglycemia, hypokalemia, cardiac arrhythmias, pulmonary edema and myocardial ischemia. government organisation
Department of Obstetrics and Gynaecology Diseases & Conditions However, under certain circumstances, e.g., as prophylaxis after myocardial infarction, there may be no acceptable alternatives to the use of beta-adrenergic blocking agents in patients with asthma.
Therefore, Terbutaline sulfate injection should be used during nursing only if the potential benefit justifies the possible risk to the newborn.Terbutaline sulfate injection is not recommended for patients under the age of 12 years because of insufficient clinical data to establish safety and effectiveness.Clinical studies of Terbutaline sulfate injection did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects.
In particular, terbutaline sulfate should not be used for tocolysis in the outpatient or home setting.
Increased fetal heart rate and neonatal hypoglycemia may occur as a result of maternal administration. ECV success rate was not significantly higher. If significant clinical improvement does not occur within 15 to 30 minutes, a second dose of 0.25 mg may be administered.
In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.Adverse reactions observed with Terbutaline sulfate injection are similar to those commonly seen with other sympathomimetic agents.
2010 See USP controlled room temperature.Protect from light by storing vials in original carton until dispensed.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
For inhalation by dry powder, advise patients and carers not to exceed prescribed dose and to follow manufacturer’s directions; if a previously effective dose of inhaled terbutaline fails to provide at least 3 hours relief, a doctor’s advice should be obtained as soon as possible.. For inhalation by nebuliser, the dose given by nebuliser is substantially higher than that given by inhaler.
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