The recommended total therapeutic dosages of Lariam tablets relative to body weight are presented in the following table:* Experience with Lariam in infants less than 3 months old or weighing less than 5 kg is limited. quinine, quinidine), or to any of the excipients contained in the formulation.- chemoprophylaxis in patients with active depression, a history of depression, generalised anxiety disorder, psychosis, suicide attempts, suicidal ideations and self-endangering behaviour, schizophrenia or other psychiatric disorders, or with a history of convulsions of any origin (see sections 4.4 and 4.5). This information is intended for use by health professionalsEach tablet contains 250 mg mefloquine (as 274.09 mg mefloquine hydrochloride).Each tablet contains 50.61 mg of lactose monohydrate.Tablet. It allows continued monitoring of the benefit/risk balance of the medicinal product.
Mefloquine should be taken with food (e.g., any meal) and with plenty of water (at least 240 mL, equivalent of 1 cup [8 ounces]).
Visit cvs.com for more details. LARIAM® 250 mg tablets Mefloquine hydrochloride 1 PRODUCT NAME Lariam 250 mg tablets 2 QUALITATIVE AND QUANTITATIVE COMPOSITION 1 tablet contains 274.09 mg racemic mefloquine hydrochloride, equivalent to 250 mg mefloquine base.
When suggestions are available use up and down arrows to review and ENTER to select. Prophylaxis with mefloquine was compared to prophylaxis with In August 2009, Roche stopped marketing Lariam in the United States.In 2006, the Australian military deemed mefloquine "a third-line drug" alternative, and over the five years from 2011 only 25 soldiers had been prescribed the drug, and only in cases of their intolerance for other alternatives.In early December 2016, the German defence ministry removed mefloquine from the list of medications it would provide to its soldiers.WRAIR has published several papers outlining ongoing efforts at that institution to make mefloquine safer by producing a drug composed of only the (+)-FC(F)(F)c2cccc1c(cc(nc12)C(F)(F)F)[C@H](O)[C@@H]3NCCCC3InChI=1S/C17H16F6N2O/c18-16(19,20)11-5-3-4-9-10(15(26)12-6-1-2-7-24-12)8-13(17(21,22)23)25-14(9)11/h3-5,8,12,15,24,26H,1-2,6-7H2/t12-,15+/m1/s1 The mean elimination plasma half-life of mefloquine is between two and four weeks. Provide symptomatic and intensive supportive treatment as required, particularly for cardiovascular disorders. Ask your pharmacist how to dispose of medications that are no longer needed or have expired.The side effects listed below are not experienced by everyone who takes this medication. Es agiert als Hormon und als Neurotransmitter zugleich. Elimination of mefloquine and its metabolites is limited by haemodialysis.Pharmaco-therapeutic group: Antiprotozoal agent, ATC code P01BC02Lariam acts on and destroys the asexual intraerythocytic forms of the human malaria parasites: Lariam is also effective against malarial parasites resistant to other antimalarials such as chloroquine and other 4-aminoquinoline derivatives, proguanil, pyrimethamine and pyrimethamine-sulphonamide combinations. Concomitant administration of mefloquine and drugs known to lower the epileptogenic threshold (antidepressants such as tricyclic or selective serotonin reuptake inhibitors (SSRIs); bupropion; antipsychotics; tramadol; chloroquine or some antibiotics) may increase the risk of convulsions (see section 4.4).Mefloquine does not inhibit or induce the cytochrome P450 enzyme system. Prophylactic treatment with mefloquine may be considered regardless the term of pregnancy but in the strict respect of the indications.- use of mefloquine as curative treatment in pregnant women is limited to the treatment of acute uncomplicated malaria when quinine is contra-indicated or in case of Plasmodium falciparum resistance to quinine.In case of unplanned pregnancy, malaria chemoprophylaxis with Lariam is not considered as an indication for pregnancy termination. In hospital settings, oxytocin is often administered with an intramuscular injection. not for stand-by therapy) and only if compelling reasons exist (see sections 4.3 and 4.5).Concomitant administration of mefloquine and anticonvulsants (e.g.
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