Fluoroquinolones should be avoided in patients with history of myasthenia gravis.Major Potential Hazard, Moderate plausibility. Clipboard, Search History, and several other advanced features are temporarily unavailable. Epub 2016 Mar 29.Appl Clin Inform. I've had life long arrhythmias and have taken Cipro a few times for various nasty infections. We report: (i) a case of torsades de pointes (Tdp) associated with oral ciprofloxacin in a patient with concomitant risk factors and (ii) a review of the literature on pharmacokinetic interactions involving ciprofloxacin resulting in cardiac arrhythmias.
Avoid the use of these agents in patients who have a history of tendon disorders or have experienced tendinitis or tendon rupture.
Unable to load your collection due to an error Sun exposure: Cipro can make your skin more sensitive to sunlight. Patients with renal impairment may be at greater risk for adverse effects from quinolones, including nephrotoxicity, due to decreased drug clearance. Although it is not expected to occur under normal circumstances with usual recommended dosages, patients who are dehydrated (e.g., due to severe diarrhea or vomiting) may be at increased risk and should be encouraged to consume additional amounts of liquid or given intravenous fluid to ensure an adequate urinary output. 2007 Aug;30(8):1043-6. doi: 10.1111/j.1540-8159.2007.00809.x.Int J Cardiol.
Major Potential Hazard, Moderate plausibility. QT prolongation may potentiate the risk of ventricular arrhythmias including ventricular tachycardia, ventricular fibrillation, and torsade de pointes. The risk appears to be greatest with grepafloxacin and sparfloxacin (both are no longer marketed in the U.S.), although cardiovascular morbidity and mortality attributable to QT prolongation have also been reported rarely with others like gatifloxacin, levofloxacin, ciprofloxacin, and ofloxacin.
As QT prolongation may be a concentration-dependent effect, it is important that the recommended dosages or infusion rates of these drugs not be exceeded, particularly in patients with renal and/or hepatic impairment.Major Potential Hazard, Moderate plausibility. Factors that may independently increase the risk of tendon rupture include strenuous physical activity, renal failure, and previous tendon disorders such as rheumatoid arthritis. Applies to: Colitis/Enteritis (Noninfectious)Pseudomembranous colitis has been reported with most antibacterial agents and may range in severity from mild to life-threatening, with an onset of up to two months following cessation of therapy. There is some evidence that pseudomembranous colitis, if it occurs, may run a more severe course in these patients and that it may be associated with flares in their underlying disease activity. Irritation Of The Stomach Or Intestines Therapy with quinolones should be administered cautiously in patients with or predisposed to seizures or other CNS abnormalities. Patients should be counseled to recognize symptoms of hypoglycemia such as headache, dizziness, drowsiness, nausea, tremor, weakness, hunger, excessive perspiration, and palpitations. The colitis is usually characterized by severe, persistent diarrhea and severe abdominal cramps, and may be associated with the passage of blood and mucus.
Applies to: Peripheral NeuropathyThe use of quinolones has been associated with an increased risk of peripheral neuropathy. Hypoglycemia and, less frequently, hyperglycemia have been reported, although the latter may also occur due to infection alone. This site needs JavaScript to work properly. Applies to: Tendonitis, Rheumatoid Arthritis, Renal Dysfunction, Organ TransplantTendonitis and ruptures of the shoulder, hand, and Achilles tendons have been reported in patients receiving quinolones, both during and after treatment.
Normal Wbc Count Coversyl, Muscoril 4mg Uses In Urdu Remeron, Can I Use Hydrocortisone Cream On Shingles Rash Sinequan, Deramaxx Megalis, Strongest Natural Antibiotic Genegra, Acyclovir Cream Where To Buy Stendra, Boswellia Serrata Supplement Lasuna, ED Nasal Spray Geodon, Amlodipine And Erectile Dysfunction Lithium, Esomeprazole Tablets Vs Capsules Motilium, Menopace Plus Boots Ranitidine, Sodium Valproate Brand Name Viagra Soft, Calcitriol Uk Lukol, Parlodel Dosage Betapace, Humana Medicaid Preferred Drug List Lariam, UK Drug Price Database Zocor, Hydrocortisone For Cold Sore Rash Asacol, Vamousse Lice Treatment Femcare, Viagra Dependency Reddit Actos, Hemosure Sensitivity And Specificity Eurax, Deep Heat And High Blood Pressure Sildalis, Isoniazid Inh Careprost, L 29 Pill Amlodipine Tricor, Cefpodoxime Vs Amoxicillin Extra Super Avana, Minoxidil 10 Percent Amazon Geodon, Can Betamethasone Cause Hair Loss Lamisil,