Significantly greater reductions in comedos and improvements, as measured by both physicians' and patients' global evaluations, were obtained with the combination agent than with clindamycin or vehicle. Please enable it to take advantage of the complete set of features! Name must be less than 100 characters Indication. Percent reductions in lesion counts after treatment for 10 weeks in these two studies are shown below:The Clindamycin and Benzoyl Peroxide Gel, 1%/5% group showed greater overall improvement than the benzoyl peroxide, clindamycin and vehicle groups as rated by the investigator.Clindamycin and Benzoyl Peroxide Gel, 1%/5% is indicated for the topical treatment of acne vulgaris.Clindamycin and Benzoyl Peroxide Gel, 1%/5% is contraindicated in those individuals who have shown hypersensitivity to any of its components or to lincomycin. Please enable it to take advantage of the complete set of features! Fifteen minutes after the face was thoroughly dry, application was made to the entire face. If this occurs, discontinue use of this medication and take appropriate measures.Clindamycin and erythromycin containing products should not be used in combination. Clipboard, Search History, and several other advanced features are temporarily unavailable.
OBJECTIVE: To evaluate long-term efficacy and safety of a fixed combination clindamycin phosphate 1.2% and benzoyl peroxide 3.75% (Clindamycin-BP 3.75%) aqueous gel in adult female patients with moderate acne vulgaris.
METHODS: Total of 20 patients, 25-63 years of age (mean [SD], 38 ± 10) with moderate acne (IGA=3) were treated with Clindamycin-BP 3.75% once-daily … The reduction in comedos and the global improvements were similar between the combination agent and benzoyl peroxide. The combination agent demonstrated significantly greater reductions in inflammatory lesions than either of its active constituents (5% benzoyl peroxide and 1% clindamycin) or vehicle when used alone. Concomitant topical acne therapy should be used with caution because a possible cumulative irritancy effect may occur, especially with the use of peeling, desquamating, or abrasive agents.The use of antibiotic agents may be associated with the overgrowth of nonsusceptible organisms including fungi. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.Safety and effectiveness of this product in pediatric patients below the age of 12 have not been established.During clinical trials, the most frequently reported adverse event in the Clindamycin and Benzoyl Peroxide Gel, 1%/5% treatment group was dry skin (12%).
The Table below lists local adverse events reported by at least 1% of patients in the Clindamycin and Benzoyl Peroxide Gel, 1%/5% and vehicle groups.The actual incidence of dry skin might have been greater were it not for the use of a moisturizer in these studies.Anaphylaxis, as well as allergic reactions leading to hospitalization, have been reported during post-marketing use of clindamycin/benzoyl peroxide products. If you are a consumer or patient please visit Amazon's Choice for clindamycin phosphate and benzoyl peroxide gel Mountain Falls 10% Benzoyl Peroxide Acne Medication, Maximum Strength, Compare to Clean & Clear, 1 Fluid Ounce (Pack of 4) 4.5 out of 5 stars 313
The SPL will be accessible from publicly available labeling repositories. Clindamycin/benzoyl peroxide is a combination of an antibiotic, clindamycin, and benzoyl peroxide, another drug that has antibacterial effects. industry .
51672-1381-5, STUDIES INDICATE A TOXIN(S) PRODUCED BY CLOSTRIDIA IS ONE PRIMARY CAUSE OF ANTIBIOTIC-ASSOCIATED COLITIS. This site needs JavaScript to work properly. at the end of this policy for important regulatory and legal information.
Print. Patients were evaluated and acne lesions counted at each clinical visit; weeks 2, 4, 6, 8 and 10.
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