0000003853 00000 n In a 1989 retrospective study, combined treatment with estrogen and cyproterone acetate [an androgen-blocker] was associated with increases in depressive mood changes (Asscheman, Gooren, & Eklund). Your doctor will:After feminizing hormone therapy, you will also need routine preventive care, including:Mayo Clinic does not endorse companies or products. 0000005943 00000 n Your doctor might discourage feminizing hormone therapy if you:Talk to your doctor about the changes in your body and any concerns you might have. Erectile function might improve with the use of oral medications such as sildenafil (Viagra) or tadalafil (Adcirca, Cialis).Before starting feminizing hormone therapy, your doctor will evaluate your health to rule out or address any medical conditions that might affect or contraindicate treatment. Typically MTF hormone therapy involves estrogen, medication to block testosterone, or a combination of the two. All rights reserved. A practical target for hormone therapy for transgender women (MTF) is to decrease testosterone levels to the normal female range (30–100 ng/dl) without supra- physiological levels of estradiol (<200 pg/ml) by administering an antiandrogen and estrogen.
"Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. %%EOF 0000008627 00000 n Feminizing hormone therapy can be done alone or in combination with feminizing surgery.Feminizing hormone therapy isn't for all transgender women, however. By the time the patient came into the care of endocrinologist Margaret Wierman, MD, she had already had her ovaries removed.
A single copy of these materials may be reprinted for noncommercial personal use only. It is used to treat the pain and inflammation in osteoarthritis, acute pain in adults, rheumatoid arthritis, ankylosing spondylitis, painful menstruation, and juvenile rheumatoid arthritis.
It works directly on tissues in your body (e.g., makes It is easier for people to maintain steady levels of estrogen on pills than with other forms of estrogen. trailer Depression has been tied to both high and low testosterone levels in women (Rohr 2002) and to the isolation of transsexuals (Rauchfleisch 1998). Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Complications of feminizing hormone therapy might include:Current evidence indicates that there is no increased risk of breast cancer.Because feminizing hormone therapy might reduce your fertility, you'll need to make decisions about future childbearing before starting treatment. The 2 major biologically active estrogens in nonpregnant humans are estrone (E1) and estradiol … 0000003892 00000 n This blocks male sex hormone (androgen) receptors and can suppress testosterone production.After six to eight weeks, you'll begin taking estrogen to decrease testosterone production and induce feminization. ESTF : Estrogens are involved in development and maintenance of the female phenotype, germ cell maturation, and pregnancy. Sometimes a progestagen is added to the mix. 0000014899 00000 n Changes caused by these medications can be temporary or permanent. Feminizing hormone therapy is also referred to as cross-sex hormone therapy.During feminizing hormone therapy, you'll be given medication to block the action of the hormone testosterone. x���A 0ð4�Fv\Gc���������z�C They also are important for many other, non-gender-specific processes, including growth, nervous system maturation, bone metabolism/remodeling, and endothelial responsiveness. 0000007898 00000 n 0000013583 00000 n 1447 29 0000012468 00000 n %PDF-1.5 %���� 1447 0 obj <> endobj • Concomitant use of CELEBREX increases lithium plasma levels.
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