How effective are azathioprine and mercaptopurine? Azathioprine may lower your body's resistance and the vaccine may not work as well or you might get the infection the vaccine is meant to prevent. Azathioprine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. The dose of this medicine will be different for different patients. Available for Android and iOS devices. Do not get close to them and do not stay in the same room with them for very long.
(Because azathioprine is an immunosuppressive medicine, it can lower the number of white blood cells in your blood, increasing the chance of getting an infection.) In addition, you should not be around other persons living in your household who receive live virus vaccines because there is a chance they could pass the virus on to you.
After six months of use, my neutrophils came back at 0.7.
Portions of this document last updated: Sept. 01, 2020Copyright © 2020 IBM Watson Health. We comply with the HONcode standard for trustworthy health information - Using these medicines together could cause serious unwanted effects. Some examples of live vaccines include measles, mumps, influenza (nasal flu vaccine), poliovirus (oral form), rotavirus, and rubella. Do not use this medicine if you are also taking mercaptopurine (Purinethol®). Using this medicine while you are pregnant can harm your unborn baby. If you have questions about this, talk to your doctor. Long-term use may increase the risk of developing some types of tumors.
Avoid being near people who are sick or have infections while you are using this medicine. Follow your doctor's orders or the directions on the label. Check with your doctor right away if you have more than one of these symptoms while you are using this medicine: severe nausea or vomiting, diarrhea, fever, rash, a general feeling of discomfort or illness, muscle or joint pain, lightheadedness or dizziness, or unusual tiredness or weakness. The amount of medicine that you take depends on the strength of the medicine. Usual Adult Dose for Crohn's Disease - Acute. Tell your doctor if you have any kind of infection before you start using this medicine. Talk to your doctor if you have questions about this. Talk to your doctor if you have concerns about this risk.
Patients not improved after 12 weeks can be considered refractory.-Azathioprine may be continued long-term in patients with clinical response.
Applies to the following strengths: 50 mg; 100 mg; 75 mgInitial dose: 3 to 5 mg/kg orally or IV once a day, beginning at the time of transplantInitial dose: 1 mg/kg (50 to 100 mg) orally or IV per day given in 1 to 2 divided dosesInitial dose: 3 to 5 mg/kg orally or IV once a day, beginning at the time of transplantLower doses may be required; however, no specific guidelines have been suggested.Dose adjustments may be required; however, no specific guidelines have been suggested.Dosage reduction or alternative therapy may be required in patients with reduced thiopurine S-methyltransferase (TPMT) activity.Data not available; approximately 45% of an azathioprine dose is removed by hemodialysis.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This medicine may increase your risk of getting certain types of cancer, especially of the skin, lymph system (lymphoma), or blood (leukemia). These could be symptoms of a serious reaction to the medicine in your bowel.
Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the m… All rights reserved. Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Do not get close to them and do not stay in the same room with them for very long. Long-term treatment with this medication is not recommended and should not be more than 6 cycles.
Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products. Azathioprine can temporarily lower the number of white blood cells in your blood, increasing the chance of getting an infection. This generally occurs after 10 years of continuous use or with a lifetime dose of 600 grams. The following information includes only the average doses of this medicine. Use sunscreen or sunblock lotions with a sun protection factor (SPF) of at least 15 on a regular basis when you are outdoors. Wear protective clothing and hats, and stay out of direct sunlight between the hours of 10 am and 3 pm Avoid sunlamps and tanning beds. If your dose is different, do not change it unless your doctor tells you to do so. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). It can also lower the number of platelets, which are necessary for proper blood clotting. Select one or more newsletters to continue. Key facts.
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