This link will take you to a third party website that is not affiliated with Cureus, Inc. (March 13, 2019) A Rare Case of DRESS (Drug Reaction with Eosinophilia and Systemic Symptoms) Syndrome with Cholecystitis in a Patient on Levetiracetam. COVID-19 is an emerging, rapidly evolving situation. "Never doubt that a small group of thoughtful, committed citizens can change the world.
It causes a skin reaction, with eosinophilia and other organ involvement. SIQ™ assesses article importance and quality by embracing the collective intelligence of the Cureus community-at-large. With that, she began to improve gradually with the disappearance of the skin rash over the next few days, resolution of the facial and the lymph node swelling, as well as a return of transaminases to the baseline over the next few weeks.Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a potentially life-threatening hypersensitivity reaction first described with phenytoin in the 1940s Final score <2 - Not DRESS, 2-3 - Possible, 4-5 - Probable, >5 - DefiniteDRESS: drug reaction with eosinophilia and systemic symptom syndrome; BSA: body surface areaIt has been shown that DRESS may be associated with acalculous cholecystitis Although rare, levetiracetam has been established to cause DRESS. She was a stay-at-home mother of one child.On physical examination, she was in mild distress due to abdominal pain, febrile to 38 degree Celsius, pulse of 110 per minute, respiratory rate of 18 breaths per min, blood pressure of 124/77 mm Hg in the right upper limb in the supine position, and oxygen saturation of 98% on room air. Name must be less than 100 characters
James J, Sammour YM, Virata AR, Nordin TA, Dumic I.Am J Case Rep. 2018 Feb 14;19:163-170. doi: 10.12659/ajcr.907464.Cent Eur J Immunol.
Please note that Cureus is not responsible for any content or activities contained within our partner or affiliate websites.Scholarly Impact Quotient™ (SIQ™) is our unique post-publication peer review rating process. The interesting features of the case include the onset of symptoms about 70 days after the initiation of levetiracetam, the lack of prominent eosinophilia and the involvement of the gall bladder, which was previously unknown with Levetiracetam. Cureus 11(3): e4245. Early discontinuation of the offending medication leads to quicker recovery.Internal Medicine, Bronx Lebanon Hospital Icahn School of Medicine at Mount Sinai, New York, USAInternal Medicine, University of Kentucky, Lexington, USASingh T, Niazi M, Karri K, et al. All registered users are invited to contribute to the SIQ™ of any published article.
2017;42(4):409-411. doi: 10.5114/ceji.2017.72821. Please enable it to take advantage of the complete set of features! 2017 Dec 28;17(1):217. doi: 10.1186/s12890-017-0564-6.Am J Case Rep. 2018 Aug 20;19:978-984. doi: 10.12659/AJCR.909569.Case Rep Med.
The family history was not significant. The symptoms resolved over the next few months after drug withdrawal.Drug reaction with eosinophilia and systemic symptoms (DRESS) syndrome is a rare but potentially life-threatening condition with a mortality rate of 10% A 36-year-old female was discovered to have an astrocytoma after she presented with new onset seizures. 2020 Jan;68(1):79. Scholary Impact Quotient™ (SIQ™) is our unique post-publication peer review rating process. (Authors cannot rate their own articles.) 2018 Jun 11;2018:1346351. doi: 10.1155/2018/1346351.
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