Itraconazole was produced to improve upon Ketoconazole to reduce the number of side effects and effectiveness for certain types of infections. This formulation is necessary because itraconazole does not dissolve well in water but dissolves well in DMSO.Itraconazole is prescribed by veterinarians to treat fungal infections of the skin, claws, bone, respiratory tract, and brain. Itraconazole is given by mouth in the form of a capsule, tablet, or liquid to treat fungal infections in cats and for off label treatment in dogs and small mammals. The most common side effects are anorexia, vomiting, liver toxicity, skin lesions, or limb and vessel swelling. No claims are made as to the safety or efficacy of mentioned preparations.
Itraconazole has been shown to cross the placenta in a rat model. A severe, dose-related ulcerative dermatitis (due to vasculitis) has been seen in 5%–10% of dogs given itraconazole in doses of 10 mg/kg. You are encouraged to speak with your prescriber as to the appropriate use of any medication. Always bring the prescription container with you when you take your pet for treatment.If you or someone else has accidentally ingested this medication call the National Capital Poison Center at 800.222.1222.Dr. This medication is effective only against fungal infections and will be ineffective if used to treat other types of infections, such as those caused by parasites, bacteria, or viruses.Topical itraconazole can kill the infective fungus at the concentrations that are reached on the surface of the eye. The veterinary oral liquid may be given with or without food, but if vomiting occurs on an empty stomach, try giving it with a small meal or treat. 's Animal Poison Control Center at 888.426.4435. Itraconazole should be used with caution in pets that are pregnant, breeding, or nursing, as its safety has not been established in these cases.The following medications should be used with caution when given with itraconazole: amphotericin B, antacids, benzodiazepines, buspirone, busulfan, calcium channel blocking agents, ciprofloxacin, cisapride, colchicine, corticosteroids, cyclophosphamide, cyclosporine, digoxin, disopyramide, doxorubicin, ergot alkaloids, fentanyl/alfentanil, HBe sure to tell your veterinarian about any medications (When using itraconazole long-term, your veterinarian will monitor your pet’s liver values. Use of them does not imply any affiliation with or endorsement by them. Ware is currently the Medical Director of University Animal Hospital (VCA) and is also the owner of two other hospitals, including Laveen Veterinary Center and Phoenix Veterinary Center. Read the labeling or ask your pharmacist for the storage requirements of the prescription you receive.Itraconazole is prescribed as an oral capsule, but other formulations are available, including oral suspension, ophthalmic solution, and topical applications. It is also important not to contaminate the medication by touching the tip with your fingers or hand. If you are asked to take two doses a day, space the doses out by taking one of the … Liver toxicity and inflammation of the blood vessels may also occur. In cats, gastrointestinal effects such as lack of appetite, vomiting, and weight loss, as well as liver toxicity can occur. Medications Its use in dogs, small mammals, and some exotics to treat fungal infections is Itraconazole is either given by mouth in the form of a capsule, tablet, or liquid solution. Other significant side effects include skin lesions that ulcerate (break open) and swelling of the extremities.
The ophthalmic preparation of itraconazole contains 1% itraconazole, 30% DMSO, and artificial tears. Wash your hands after giving your horse this medication.If you suspect your horse or another animal was overdosed accidentally or has eaten this medication inadvertently, contact your veterinarian or the A.S.P.C.A. It is particularly effective against Aspergillus, one of the more-common fungal pathogens.
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