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informational and educational purposes only. Your doctor may occasionally change your dose. You may report side effects to FDA at 1-800-FDA-1088.Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).You should not use diclofenac if you are allergic to it, or if you have ever had an To make sure diclofenac is safe for you, tell your doctor if you have:It is not known whether diclofenac passes into breast milk or if it could harm a nursing baby. Indications/Uses : Treatment of community-acquired pneumonia, UTI including complicated UTI, skin & soft tissue infections. This website also contains material copyrighted by 3rd parties.
Call your doctor for medical advice about side effects. and formulary information changes. People with uncontrolled high blood pressure (hypertension). Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect.
Indicated for acute and maintenance treatment of major depressive disorder (MDD) 10 mg PO qDay; may increase to 20 mg/day after 1 weekIndicated for acute treatment of generalized anxiety disorder (GAD) 10 mg PO qDay; may increase to 20 mg/day after 1 week; maintain at lowest effective dose and assess need of therapy periodically if extended therapy required10 mg PO qDay; may increase to 20 mg/day after 1 week; maintain at lowest effective dose and assess need of therapy periodically if extended therapy requiredSecondary to Depression: 5-20 mg PO over 8 week periodSecondary to panic disorder in women: 5-10 mg PO over 8 week period10 mg PO qDay; may increase to 20 mg PO qDay after 4 weeks if symptoms not adequately controlledFor extended therapy, maintain at lowest effective dose and assess periodically the need for continued therapy≥12 years: 10 mg PO qDay; may increase dose after at least 3 weeks; not to exceed 20 mg/dayFor extended therapy, maintain at lowest effective dose and assess periodically the need for continued therapy10 mg/day is recommended for most elderly; no additional benefits seen at 20 mg/day doseThe elderly are more prone to SSRI/SNRI-induced hyponatremiaBlood and lymphatic system disorders: Anemia, agranulocytosis, aplastic anemia, hemolytic anemia, idiopathic thrombocytopenia purpura, leukopenia, thrombocytopeniaCardiac disorders: Atrial fibrillation, bradycardia, cardiac failure, myocardial infarction, tachycardia, torsades de pointes, ventricular arrhythmia, ventricular tachycardiaEndocrine disorders: Diabetes mellitus, hyperprolactinemia, SIADHEye disorders: Angle closure glaucoma, diplopia, mydriasis, visual disturbanceGastrointestinal disorder: Dysphagia, gastrointestinal hemorrhage, gastroesophageal reflux, pancreatitis, rectal hemorrhageGeneral disorders and administration site conditions: Abnormal gait, asthenia, edema, fall, feeling abnormal, malaiseHepatobiliary disorders: Fulminant hepatitis, hepatic failure, hepatic necrosis, hepatitisImmune system disorders: Allergic reaction, anaphylaxisInvestigations: Bilirubin increased, decreased weight, QT prolongation, hepatic enzymes increased, hypercholesterolemia, INR increased, prothrombin decreasedMetabolism and nutrition disorders: Hyperglycemia, hypoglycemia, hypokalemia, hyponatremiaMusculoskeletal and connective tissue disorders: Muscle cramp, muscle stiffness, muscle weakness, rhabdomyolysisNervous system disorders: Akathisia, amnesia, ataxia, choreoathetosis, cerebrovascular accident, dysarthria, dyskinesia, dystonia, extrapyramidal disorders, grand mal seizures (or convulsions), myoclonus, nystagmus, Parkinsonism, restless legs, seizures, syncope, tardive dyskinesia, tremorPregnancy, puerperium and perinatal conditions: Spontaneous abortionPsychiatric disorders: Acute psychosis, aggression, agitation, anger, anxiety, apathy, completed suicide, confusion, depersonalization, depression aggravated, delirium, delusion, disorientation, feeling unreal, hallucinations (visual and auditory), mood swings, nervousness, nightmare, panic reaction, paranoia, restlessness, self-harm or thoughts of self-harm, suicide attempt, suicidal ideation, suicidal tendency Renal and urinary disorders: Acute renal failure, dysuria, urinary retentionReproductive system and breast disorders: Menorrhagia, priapismRespiratory, thoracic and mediastinal disorders: Dyspnea, epistaxis, pulmonary embolism, pulmonary hypertension of the newbornSkin and SC tissue disorders: Alopecia, angioedema, dermatitis, ecchymosis, erythema multiforme, photosensitivity reaction, Stevens Johnson syndrome, toxic epidermal necrolysis, urticariaVascular Disorders: Deep vein thrombosis, flushing, hypertensive crisis, hypotension, orthostatic hypotension, phlebitis, thrombosisConflicting evidence regarding use of SSRIs during pregnancy and increased risk of persistent pulmonary hypertension of the newborn, or PPHN (see Pregnancy)In neonates exposed to SNRIs/SSRIs late in third trimester: risk of complications such as feeding difficulties, irritability, and respiratory problemsPrior to initiating treatment, screen patients for any personal or family history of bipolar disorder, mania, or hypomaniaCaution with seizure disorder, bipolar mania, severe renal impairment; not FDA approved for the treatment of bipolar depressionSNRIs/SSRIs have been associated with the development of SIADH; hyponatremia has been reported rarelyActivation of mania/hypomania reported in a small proportion of patients with major affective disorders treated with citalopram and other marketed drugs effective in treatment of major depressive disorderMay worsen psychosis in some patients and precipitate a shift to mania or hypomania in patients with bipolar disorderConsider changing therapeutic regimen, in patients whose depression is persistently worse, or who are experiencing emergent suicidal thoughts or behaviorsRisk of mydriasis; may trigger angle closure attack in patients with angle closure glaucoma with anatomically narrow angles without a patent iridectomyBone fractures are associated with antidepressant therapy; consider the possibility of a fracture in patients with unexplained bone pain, swelling, or bruisingPrescribe the smallest quantity of tablets consistent with good patient care and alert family or caregiver to monitor for emergence of suicidality and associated behaviors (anxiety, agitation, panic attacks, insomnia, hostility, akathisia, impulsivity, irritability)SSRIs/SNRIs increase risk of abnormal bleeding (further increased if concomitant aspirin, NSAIDs or anticoagulants, or hemorrhagic diathesis)Prolongation of QT interval and ventricular arrhythmias reported, especially in female patients with preexisting QT prolongation or other risk factorsRisk of cognitive and motor function impairment; use caution when operating heavy machineryUse with caution in patients with history of seizure disorders or conditions predisposing to seizures including brain damage and alcoholismGradually taper dose before discontinuation; abrupt discontinuation may cause dysphoric mood, dizziness, sensory disturbances, agitation, confusion, anxiety, headache, insomnia, tinnitus, seizures, irritabilityThere are no adequate and well-controlled studies in pregnant women; therefore, use during pregnancy only if the potential benefit justifies the potential risk to the fetusIn some cases, the clinical picture is consistent with serotonin syndrome Limited data from women taking 10-20 mg escitalopram showed that exclusively breast-fed infants receive a ~3.9% of the maternal weight-adjusted dose of escitalopram and 1.7% of the maternal weight-adjusted dose of desmethylcitalopramCaution should be exercised and breastfeeding infants should be observed for adverse reactions when administered to a nursing womanA: Generally acceptable.
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