It involves taking HIV medications as soon as possible after a potential exposure to HIV. Post-exposure prophylaxis, or PEP, is a way to help prevent the transmission of HIV in an HIV-negative person who may have been recently exposed to the virus. The Canadian guidelines outline practical advice for physicians providing PEP, including how to assess risk in people who present for PEP, how to provide monitoring and follow-up, and recommended drug regimens.People starting PEP may be offered a “starter pack” of pills, so that PEP can be started right away, along with a prescription that needs to be filled to receive the full 28-day course of medications. If the person is HIV positive (but doesn’t know it) they should be referred to HIV care and treatment.If rapid HIV testing (which gives results within a matter of minutes) is not available, the test result may not be ready for one to two weeks; however, PEP will be started immediately. When a person presents for PEP at a clinic or emergency room, a risk assessment will determine whether PEP should be started based on their risk for HIV infection. PEP should be discontinued if the PEP user tests HIV positive, or if the contact person is confirmed to be HIV negative.PEP medications need to be taken consistently and correctly—every day for four weeks—or the risk of HIV infection will increase.
• The 3rd drug can be added after consultation with an expert. For PEP to be effective, a person must have high adherence to the full course of PEP drugs and should have no further exposures to HIV while taking PEP.PEP consists of a combination of three HIV medications that an HIV-negative person takes for four weeks to reduce their risk of getting HIV PEP interferes with the pathways that HIV uses to cause a permanent infection in the body. For HIV to cause infection the virus must enter the body, infect certain immune cells, make copies of itself (replicate) within these immune cells, then spread throughout the body.When PEP is taken, the HIV drugs get into the bloodstream and the genital and rectal tissues. The nature and severity of the side effects depend on the type of drugs prescribed and the person who is taking them. Although occupational PEP is normally covered by workplace insurance, coverage for non-occupational PEP varies across Canada. It must be started within 72 hours of exposure to HIV. 6. l Table 54: Dosages of the drugs for PEP Medication 2-d3-drugrug regimenregimen Zidovudine (AZT) 300300 mgmg twice aa dayday … Assessment of HIV risk is based on the type of exposure and the likelihood that the contact person was HIV positive.PEP may not be recommended if a person’s chance of getting HIV is low, either because their exposure carries no risk or very low risk of transmission (for example, oral sex) or because it is unlikely that the contact person is HIV positive.PEP is not intended for people with ongoing exposures to HIV. The risk of HIV acquisition from a given exposure depends on the likelihood the source has transmissible HIV infection, and the biological risk of HIV transmission based on the exposure that has … This includes:An HIV-negative person who thinks they may have been exposed to HIV within the last 72 hours should consider taking PEP. This guideline is intended to guide health care providers caring for persons who have experienced significant exposure to blood and/or body fluids in the work place or community setting. The use of PEP is only intended to reduce the risk of infection associated with one exposure. Annex F: Systematic review: which ART regimen to switch to when failing first/line treatment pdf, 1.6Mb Annex G: Safety and efficacy of antiretroviral drugs for post-exposure prophylaxis pdf, 963Kb Annex H: Indeterminate results during HIV early infant diagnosis testing: a meta-analysis and review of the literature pdf, 1.4Mb Most (but not all) emergency departments will have PEP “starter packs” available.Anti-HIV drugs are expensive: a month-long course of PEP can cost $900 or more, depending on the drugs used. These include emergency departments, sexual health clinics and other clinics serving populations at increased risk of HIV.The decision to provide PEP lies with the healthcare provider and is made on a case-by-case basis. PEP is meant to be used for emergencies only and should not be used as an ongoing HIV prevention strategy.A person with low adherence to PEP, who acquires HIV while taking PEP, could develop resistance to the drugs in PEP.
Milk Thistle And Azathioprine Aricept, Zoloft And High Prolactin Levels Avapro, Piracetam Sleep Kamagra Flavored, Asthalin Contraindications Cialis Professional, Ortho Tri Cyclen Generic Vs Brand Name Maxolon, Permethrin Mechanism Of Action Usmle Omnicef, Gluconorm Dosage Myambutol, Chloroquine Phosphate Buy Online Amoxil, Topical Compounding Recipes Robaxin, Joker Couple Costume Amoxil, Pill Identifier Wellbutrin, Gabapentin For Sciatica Uk Wellbutrin, Gourmet Ice Cream Toppings Hydrea, Nasal Spray Burning Roof Of Mouth Oxytrol, Express Scripts Lozol, Zyrtec And Keppra Mircette, Olmesartan Medoxomil 40 Mg Reviews Arcoxia, Elimite Cream For Scabies Keflex, Sar Of Fluoroquinolones SlideShare Wellbutrin, Pepcid Complete For Gerd, Bipolar Medication Side Effects Proscar, Best Retinol Cream For Acne Aralen, Petsmart Actos,