These medicines may interact and cause very harmful effects. The drug is metabolised in the liver by cytochrome P450 isoenzymes, principally CYP1A2, to demethylated and hydroxylated products.
Other medications can affect the removal of theophylline from your body, which may affect how theophylline works. Appearance of cardiac adverse effects is generally an indication of theophylline toxicity, although patients with a history of tachyarrhythmias may be more susceptible to the chronotropic effect of these drugs. An evaluation of the quinolone-theophylline interaction using the Food and Drug Administration spontaneous reporting system. Select one or more newsletters to continue. Cimetidine-theophylline interaction: effects of age and cimetidine dose. Tobacco and marijuana smoke (including secondhand exposure) generally reduces, while caffeine increases, blood levels. Drug-Drug Interactions: Theophylline interacts with a wide variety of drugs.
Drug Interactions. When theophylline is given with enteral (tube) feedings, blood levels may be decreased due to interference with its absorption. Includes High Blood Pressure (Hypertension) ... Sessler CN "Theophylline toxicity: clinical features of 116 consecutive cases." This information is generalized and not intended as specific medical advice.
Am J Med 88 (1990): 567-76 ... Aerolate SR (theophylline) drug interactions. Ask your doctor before using theophylline together with caffeine. Select one or more newsletters to continue. Talk to a healthcare professional if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. It is best to avoid smoking and to limit caffeine consumption during theophylline therapy. Drug-Food Interactions: Taking Theophylline extended-release tablets immediately after ingesting a high fat content meal (45 g fat, 55 g carbohydrates, 28 g protein, 789 calories) may result in a somewhat higher C max and delayed T max and a somewhat greater extent of absorption … Using these medications together may increase some of the side effects of theophylline.
Do not start, stop, or change the dosage of any medicine before checking with them first.Selected from data included with permission and copyrighted by First Databank, Inc.
Appearance of cardiac adverse effects is generally an indication of theophylline toxicity, although patients with a history of tachyarrhythmias may be more susceptible to the chronotropic effect of these drugs. Ask your doctor before using theophylline together with caffeine. Older age may make this interaction worse.Your healthcare professionals may already be aware of this interaction and may be monitoring you for it. A product that may interact with this drug is: riociguat. Contact your healthcare professional (e.g.
Ther Drug Monit 1985;7(4):426-34.
This can cause nausea, vomiting, insomnia, tremors, restlessness, uneven heartbeats, and seizure (convulsions). Clinical monitoring of serum drug concentrations is recommended to prevent toxicity.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
Caution is also advised in patients with hypertension, hyperthyroidism, angina pectoris, or recent myocardial infarction, since high dosages of the drugs are associated with positive inotropic as well as chronotropic effects. Inhaled corticosteroids are the preferred asthma maintenance treatment during pregnancy due to the potential toxicities of theophylline and the propensity for drug interactions that can reduce theophylline clearance. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.Things to remember when you fill your prescription.WebMD does not provide medical advice, diagnosis or treatment. Cimetidine-theophylline interaction: effects of age and cimetidine dose.
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