2 0 obj Consequently, the patients with cancer enrolled in the study were much healthier and had much lower mortality than those enrolled in the CLOT trial (6% and 7.7% at 3 months for apixaban and enoxaparin/warfarin in the AMPLIFY trial vs 39% and 41% at 6 months for dalteparin and oral anticoagulant in the CLOT trial, respectively). Guideline on Oral Anticoagulation Page 3 of 12 Revised: November 2019 Review Date: October 2022 1.
The effect of warfarin is measured by a blood test referred to as INR (international normalised ratio). )��� `�Ö�R�8d�� ���������|q?��������U1�|�iu���O�����������z�|�l����ɋOO���Q���N>}y�DMj�OML3�T[Y����zr���������?�O?=}��N^��rr���bu���ZO��gm������N��?O|�5�다gl�k�\eUޢ�������L�� �&�7]������z�N�8S&|�|v� �O���z1;��]¿��TVK�(�ڪis�&� ZW31�j�� �v��۞�1��7%"5hw`�M]W���q���Tu���p���t��4�m�%&'uU�ZO>-�^-"X�*�QSkv���:��+�#���pb�&���:����ǡ��0u�Rm��r�[�t;��ng'�J�q��ܜk[Y#���'f�M����Z[���c3j۪5e��������L� X��Gdg���&���A�/K� s2H���@�[̢��j����"���+��T̾.�{?�]e stream ESC Clinical Practice Guidelines aim to present all the relevant evidence to help physicians weigh the benefits and risks of a particular diagnostic or therapeutic procedure on Atrial Fibrillation.
chair), for the CCS Atrial Fibrillation Guidelines Committee* * For a complete listing of the primary and secondary members of the CCS Atrial Fibrillation Guidelines Committee along with their affiliations, see the end of this document. %���� NB There are no dosing guidelines for patients with an INR 1.4 Contraindications to warfarin anticoagulation
L>����{Բ����� ��9E����8��%�Z��H� �F8P+A�ul(f"� 6�i��V� Ԍ� �$Ȕt�^���T�b��k���+h۔+Ŭ��}��P-���z�6�糷��Ѝ�ySN�(�"}��]�ҧ�-�3�M洢�U�d�i�P�g��gڀA;i��P���}��~�¨����h� *h�,��D�D�D�"g5"g�nQbQbV�RY�����Zlg` �!#s h�24�0V0P���w,-��/��M,��/���K�����w.JM,���sI,I�p�220�002�045221�����f&�秕�S�OK�LNU�/JQ0200����OA�4064240131�(�O)MN�o��@� �3� INR is a measure of how much longer it takes the blood to clot when oral anticoagulation is used. Clinical Excellence Commission December 2018 INTRODUCTION This clinical guideline is intended to assist clinicians with the inpatient and outpatient management of adult patients (over 16 years of age) undergoing procedures* who are taking anticoagulant or antiplatelet therapy. endstream endobj 1763 0 obj <>stream The safety and efficacy of warfarin is critically dependent on maintaining the INR within <> 3 0 obj The guideline panel developed and graded the recommendations and assessed the certainty in the supporting evidence following the GRADE approach. The guideline panel developed and graded the recommendations and assessed the certainty in the supporting evidence following the GRADE approach. %PDF-1.5 This guideline outlines a standardised approach for: endobj h�24�0R0P���w�/�+Q0����L)�64�0�)�Ic0i |�'6�簟8�FW��{��6��$���]�I��{˵�5zvi�qSi���b�����M�? The recommendations indicated are the most '��@���� �X'�g%)�ᇼ�4�27������]iB�3jVOs֩�يL�������`�6�� 4r ޠw���"DW��=����aq����'z\�(D���Ԣ����Q����=0+N&��ia�W�����'� '̼ݿ>0�8ژ�����5�v���p�uzJ�/�,�Y�j��"hT&��L�R�����7�D�B�yD�����Nr�BzJ����7�[�WQ�=�2�B:�vzR�W��;U ;����f����-�����-tە���ج�r�Lci�����SX�����W7~�5�e+�����������R����i���������7������S� ��E <>/XObject<>/ProcSet[/PDF/Text/ImageB/ImageC/ImageI] >>/Annots[ 21 0 R] /MediaBox[ 0 0 596.04 842.04] /Contents 4 0 R/Group<>/Tabs/S/StructParents 0>> endobj 1�PF
4,21 Based on these results, the NCCN Guidelines … x��=�r7���?��Z����V�U�f�Ml��Tꔳ5�t"� %PDF-1.6 %���� h��S�j�0~������4-���nS�@��4ԀVi�po���vsW�#|m��w�9I�s�,Is�8 the setting of over anticoagulation, is a major concern.
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