This medicine may interact with other drugs or health problems. Patients should be advised not to increase the dose or dosing frequency, as studies have not demonstrated increased effectiveness at higher doses and somnolence may occur. An increase in the mean elimination half-life of desloratadine in patients with hepatic impairment was observed. To help you remember, take it at the same times each day. How to use Albuterol Sulfate Tablet. Other reported clinical experience has not identified differences between the elderly and younger patients. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Use these dosage charts for infants and children under 12 years old:The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Tell your However, the CA single dose of either 2.5 mL or 1.25 mL of CLARINEX Syrup containing 1.25 mg or 0.625 mg, respectively, of desloratadine was administered to subjects 6 to 11 months of age and 12 to 23 months of age. Available for Android and iOS devices. The oral median lethal dose in mice was 353 mg/kg (estimated desloratadine exposures were approximately 290 times the human daily oral dose on a mg/mThe recommended dose of CLARINEX Tablets or CLARINEX RediTabs Tablets is one 5 mg tablet once daily or the recommended dose of CLARINEX Syrup is 2 teaspoonfuls (5 mg in 10 mL) once daily.The recommended dose of CLARINEX Syrup is 1 teaspoonful (2.5 mg in 5 mL) once daily or the recommended dose of CLARINEX RediTabs Tablets is one 2.5 mg tablet once daily.The recommended dose of CLARINEX Syrup is ½ teaspoonful (1.25 mg in 2.5 mL) once daily.The recommended dose of CLARINEX Syrup is 2 mL (1.0 mg) once daily.The age-appropriate dose of CLARINEX Syrup should be administered with a commercially available measuring dropper or syringe that is calibrated to deliver 2 mL and 2.5 mL (½ teaspoon).In adult patients with liver or renal impairment, a starting dose of one 5 mg tablet every other day is recommended based on pharmacokinetic data.
In pharmacokinetic studies (n=3748), approximately 6% of subjects were poor metabolizers of desloratadine (defined as a subject with an AUC ratio of 3-hydroxydesloratadine to desloratadine less than 0.1, or a subject with a desloratadine half-life exceeding 50 hours). In subjects 6 months to 11 months of age, adverse events reported for CLARINEX and placebo in at least 2 percent of subjects receiving CLARINEX Syrup and at a frequency greater than placebo were upper respiratory tract infections (21.2%, 12.9%), diarrhea (19.7%, 8.1%), fever (12.1%, 1.6%), irritability (12.1%, 11.3%), coughing (10.6%, 9.7%), somnolence (9.1%, 8.1%), bronchitis (6.1%, 0%), otitis media (6.1%, 1.6%), vomiting (6.1%, 3.2%), anorexia (4.5%, 1.6%), pharyngitis (4.5%, 1.6%), insomnia (4.5%, 0%), rhinorrhea (4.5%, 3.2%), erythema (3.0%, 1.6%), and nausea (3.0%, 0%). advice about side effects. No images are available for this medication.Are you planning to see a doctor about switching your medication?Are you planning to see a doctor about switching your medication?Selected from data included with permission and copyrighted by First Databank, Inc. Do not store in the bathroom. Subjects who are poor metabolizers of desloratadine cannot be prospectively identified and will be exposed to higher levels of desloratadine following dosing with the recommended dose of desloratadine. In subjects 2 to 5 years old, a single dose of 2.5 mL of CLARINEX Syrup containing 1.25 mg of desloratadine resulted in desloratadine plasma concentrations similar to those achieved in adults administered a single 5 mg CLARINEX Tablet. There was no evidence of histamine-induced skin wheal tachyphylaxis within the desloratadine 5 mg group over the 28-day treatment period. It also contains granulated sugar, natural and artificial flavor for bubble gum and FDC Yellow #6 dye.Desloratadine is a white to off-white powder that is slightly soluble in water, but very soluble in ethanol and propylene glycol. Dosing recommendation for children with liver or renal impairment cannot be made due to lack of data.Place CLARINEX (desloratadine) RediTabs Tablets on the tongue and allow to disintegrate before swallowing.
The results of a population pharmacokinetic analysis indicated that a dose of 1 mg for subjects aged 6 to 11 months and 1.25 mg for subjects 12 to 23 months of age is required to obtain desloratadine plasma concentrations similar to those achieved in adults administered a single 5 mg dose of CLARINEX Syrup.The CLARINEX RediTabs Tablet 2.5 mg tablet has not been evaluated in pediatric patients. Other drugs may interact with desloratadine, including prescription and over-the-counter medicines, Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Clarinex only for the indication prescribed.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Copyright 1996-2020 Cerner Multum, Inc.
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