The incidence of convulsions, in children less than 5 years, is about 60% when the oral dose ingested exceeds 40 mg/kg.In the management of acute overdosage with Cyclizine lactate Solution for injection, gastric lavage and supportive measures for respiration and circulation should be performed if necessary. Cyclizine Lactate is contraindicated in the presence of acute alcohol intoxication. Hypersensitivity to the active substance or to any of the excipients listed in section 6.1. Continue typing to refine. This contraindication is often extended to other opioids. 4.5 Interaction with other medicinal products and other forms of interaction6.6 Special precautions for disposal and other handling9. Selegiline is contraindicated for use with meperidine (DEMEROL & other trade names). Hypersensitivity to the active substance or to any of the excipients listed in section 6.1.
There are no adequate nonclinical studies of the effects of cyclizine on fertility.Studies designed to detect drowsiness did not reveal sedation in healthy adults who took a single Patients should not drive or operate machinery until they have determined their own response.Although there are no data available, patients should be cautioned that Cyclizine lactate Solution for injection may have additive effects with alcohol and other central nervous system depressants, e.g. Convulsions should be controlled in the usual way with parenteral anticonvulsant therapy.Pharmacotherapeutic group: Piperazine derivatives, ATC code: R06AECyclizine produces its antiemetic effect within two hours and lasts approximately four hours.In healthy adult volunteers the administration of a single oral dose of 50 mg cyclizine resulted in a peak plasma concentration of approximately 70 ng/mL occurring at about two hours after drug administration. hypnotics, tranquillisers, anaesthetics, antipsychotics, barbiturates.Cyclizine lactate Solution for injection enhances the soporific effect of pethidine.Cyclizine lactate Solution for injection may counteract the haemodynamic benefits of opioid analgesics.Because of its anticholinergic activity, cyclizine may enhance the side-effects of other anticholinergic drugs, and may have an additive antimuscarinic action with other antimuscarinic drugs, such as atropine and some antidepressants (both tricyclics and MAOIs).Cyclizine lactate Solution for injection may mask the warning signs of damage caused by ototoxic drugs such as aminoglycoside antibacterials.In the absence of any definitive human data, the use of Cyclizine lactate Solution for injection in pregnancy is not advised.Cyclizine is excreted in human milk, however, the amount has not been quantified.The effects of Cyclizine lactate Solution for injection on human fertility are unknown. Cyclizine Hydrochloride 50 mg Tablets.
In such patients, cyclizine may cause a fall in cardiac output associated with increases in heart rate, mean arterial pressure and pulmonary wedge pressure.There have been reports of abuse of cyclizine, either oral or intravenous, for its euphoric or hallucinatory effects. Eldepryl capsules are used together with levodopa and carbidopa to treat symptoms of Parkinson's disease. Keep this leaflet. Apply 1 drop at least every 2 hours in severe infection, reduce frequency as infection is controlled and continue for 48 hours after healing, frequency of eye drops depends on the severity of the infection and the potential for irreversible ocular damage; for less severe infection 3–4 times daily is generally sufficient. Contraindications Cyclizine Lactate may counteract the haemodynamic benefits of opioid analgesics. Cyclizine is also known as: Bonine for Kids, Cyclivert, MarezineAnimal studies have revealed evidence of malformations (e.g., cleft palate, cephalic abnormalities) at doses above 25 to 50 mg/kg/day.
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