The anticholinergics tolterodine and oxybutynin are well established in the management of overactive bladder. Some features of the site may not work correctly.Comparison of efficacy and tolerability of pharmacological treatment for the overactive bladder in women: A network meta-analysis.Efficacy and safety of mirabegron, a &bgr;3‐adrenoceptor agonist, in patients with detrusor hyperactivity and impaired contractilityEfficacy and safety of mirabegron, a &bgr;3‐adrenoceptor agonist, in patients with detrusor hyperactivity and impaired contractilityComparison of efficacy and tolerability of pharmacological treatment for the overactive bladder in women: A network meta-analysis.Clinical efficacy and safety of tolterodine in the treatment of overactive bladder: a pooled analysis.Comparison of fesoterodine and tolterodine extended release for the treatment of overactive bladder: a head‐to‐head placebo‐controlled trialComparison of fesoterodine and tolterodine in patients with overactive bladderEffectiveness and tolerability of extended-release oxybutynin vs extended-release tolterodine in women with or without prior anticholinergic treatment for overactive bladderEstimated economic costs of overactive bladder in the United States.How widespread are the symptoms of an overactive bladder and how are they managed? Oxybutynin and tolterodine. Side Effects. Make sure that infection is ruled out - since this is one of the more common causes of spasm. A population‐based prevalence studyPrevalence and burden of overactive bladder in the United StatesPsychometric validation of an overactive bladder symptom and health-related quality of life questionnaire: The OAB-qRandomized, double-blind placebo controlled trial of the once daily antimuscarinic agent solifenacin succinate in patients with overactive bladder.Solifenacin and tolterodine are equally effective in the treatment of overactive bladder symptoms.By clicking accept or continuing to use the site, you agree to the terms outlined in our ScienceDirect ® is a registered trademark of Elsevier B.V.Tolterodine versus oxybutynin in the treatment of urge urinary incontinence: A meta-analysisPresented at the American Urogynecologic Society Twenty-first Annual Scientific Meeting, Hilton Head, SC, October 26-28, 2000.ScienceDirect ® is a registered trademark of Elsevier B.V.
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Solifenacin and oxybutynin showed improved efficacy, but more adverse effects were also reported. Tolterodine works by stopping sudden bladder muscle contractions and increasing the volume of urine that your bladder can hold. Although not all of these side effects may occur, if they do occur they may need medical attention. Results: Solifenacin and tolterodine were equally effective as treatments for OAB.
Reprint requests: Marie-Andrée Harvey, MD, Department of Obstetrics and Gynecology, University of Ottawa, Ottawa Hospital–General Campus, 501 Smyth Rd, Box 802, Ottawa, Ontario, Canada K1H 8L6.We use cookies to help provide and enhance our service and tailor content and ads.
You are currently offline. This helps to control the release of urine and eases your symptoms. Objective: To compare tolterodine with oxybutynin in treatment of urge incontinence.Study Design: A systematic review, following Cochrane methods, was performed to retrieve results of randomized trials that compared tolterodine with oxybutynin in adults with urge incontinence.
J.K. Aronson, in Side Effects of Drugs Annual, 2009. Ditropan (oxybutynin chloride) and Detrol (tolterodine tartarate) are antispasmodics and anticholinergics used to treat symptoms of overactive bladder, such as frequent or urgent urination, incontinence (urine leakage), and increased nighttime urination.
These include oxybutynin (Ditropan), tolterodine tartrate (Detrol), hyoscyamine (Levsinex, Levbid, Cystospaz), flavoxate hydrochloride (Urispas), and imipramine (Tofranil). In addition to a 16.5% increase in continuation over the first month, tolterodine was the more economical choice overall, with commercially insured patients spending less on tolterodine ER than oxybutynin. Dry mouth was reported in 35% of the subjects taking solifenacin vs. 83% of the subjects taking oxybutynin (p< 0, 0001). These medications lengthen the intervals between urination and decrease urgency. In addition to these uses, tolterodine can also be prescribed on the advice of a specialist for older children (over 5 years of age) to help reduce bedwetting caused by an overactive bladder. Composite point estimates of efficacy (episodes of incontinence per 24-hour period, frequency, and voided …
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