3. Drug Interaction Classification Systems: Significance Rating (A) Criteria Management Rating (B) Criteria: 0: Not listed 0: Not listed: 1: Severity - Major: The effects are potentially life-threatening or capable of causing permanent damage. 1994;121:676–83. While the risk of major bleeding is low, you need to be aware of potential problems. Warfarin and Antibiotic Interactions This form is for informational use only and should not supersede clinical judgment. We comply with the HONcode standard for trustworthy health information - This complication occurs within a few days of starting warfarin treatment.
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Never take a double dose.If you follow your doctor's dosing instructions and tell all your health care providers that you take warfarin, you'll be at a much lower risk of dangerous interactions and side effects. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.© 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Warfarin reduces the formation of blood clots. Available for Android and iOS devices. Older adults are generally at greater risk of bleeding, and taking other blood-thinning medication also increases your risk.A number of people who take warfarin are at a higher risk of bleeding because of their genetics make them more sensitive to warfarin. Generic Brand Severity Effect on INR Notes Top Commonly Used Antibiotics in 2017 These include incorrect usage, interactions with certain drugs, supplements or foods, changes in diets, and illnesses. Reference: Lexi-Comp Online, Hudson, Ohio: Lexi-Comp, Inc.; February 3, 2017. Ann Intern Med. More-serious bleeding may be inside the body (internal).Seek immediate help if you have any of the following:Rarely, warfarin can cause the death of skin tissue (necrosis). Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Therefore, people who take several drugs are at the greatest risk for interactions. Warfarin works by disrupting the role of vitamin K in a complex series of molecular events that cause blood clotting. This list covers only some interactions. If you don't remember until the next day, call your doctor for instructions. Use WebMD’s Drug Interaction Checker tool to find and identify potentially harmful and unsafe combinations of prescription medications by entering two or more drugs in question. If you take warfarin, it's important to have a consistent amount of vitamin K in your diet. Mayo Clinic is a nonprofit organization and proceeds from Web advertising help support our mission. Whenever two or more drugs are being taken, there is a chance that there will be an interaction among the drugs. But it's also important to remember that warfarin can result in serious side effects.The same action of warfarin that prevents blood clotting can result in bleeding. These include incorrect usage, interactions with certain drugs, supplements or foods, changes in diets, and illnesses.If your doctor prescribes warfarin for you, make sure you understand what the potential side effects are and how to help prevent them.The main risk is bleeding. Several popular herbal supplements interact with common heart medications. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Talk to your doctor, nurse or pharmacist if you have any concerns about warfarin.Mayo Clinic does not endorse companies or products. Warfarin is used to treat or prevent blood clots in veins or arteries, which can reduce the risk of stroke, heart attack, or other serious conditions.. Warfarin may also be used for purposes not listed in this medication guide. Warfarin treatment is a careful balance, and certain factors can tip the balance, increasing the risk of bleeding. More than 120 drugs and foods that can interact with warfarin have been identified.Common drugs that can interact with warfarin include:Common supplements that can interact with warfarin include:Common foods and drinks that might interact with warfarin include:It's important to understand the role of vitamin K in warfarin treatment and a healthy diet. Type in a drug name to check for interactions with Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Some mixtures of medications can lead to serious and even fatal consequences.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
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