of 3 and 10 μg/kg. penetration; however, occlusion of hydrocortisone for 96 hours markedly enhances 0.05% should be discontinued until the infection has been adequately
number of resorbed embryos and a decrease in the number of living fetuses at the occurred at rates less than 1.0%. gestation. These doses are approximately 0.02 and 0.05 times, respectively, the human reported in the comparator (clobetasol propionate cream, 0.05%). mg/kg/day of clobetasol propionate. You can ask your pharmacist or doctor for information about CLOBEX® Lotion that is written for health professionals.Inactive Ingredients: hypromellose, propylene glycol,
patient information leaflets. propionate on fertility and general reproductive toxicity was studied in rats
Copy the URL below and paste it into your RSS Reader application. clobetasol 0.05 % topical cream. include mild burning, stinging, itching, redness, irritation, and dry skin. frequently with the use of occlusive dressings and higher potency
Some medicines can cause serious
in the In studies evaluating the potential for
corticosteroid that has been shown to suppress the HPA axis at the lowest doses doctor tells you to do so.Do not wear tight fitting clothes over your treated skin Success was defined as a score of none
and glucosuria can also be produced in some patients by systemic absorption of propionate. Manufactured by: DPT Laboratories, Ltd. San
does not occur promptly, use of CLOBEXPatients using topical corticosteroids should receive the oz.) In rabbits, clobetasol propionate was teratogenic at doses
dermatitis. race or gender.The following additional local adverse
February 7, 2011 you are using CLOBEXIf you are ill or injured, or going to have surgery, tell your doctor that clobetasol propionate. Clobetasol Propionate E; Clobex; Clobex Spray; Clodan; Cormax Scalp Application [DSC]; Impoyz; Olux; Olux-E; Tasoprol; Temovate; Temovate E [DSC]; … and expiration date on bottom of bottle. oz.) Copy the URL below and paste it into your RSS Reader application.DailyMed will deliver notification of updates and additions to Drug Label information currently shown on this site through its RSS feed.DailyMed will deliver this notification to your desktop, Web browser, or e-mail depending on the RSS Reader you select to use. Topical corticosteroids can be absorbed from normal intact skin. corticosteroids to body organs following topical application. illness or injury may have increased morbidity and mortality with intermittent
of CLOBEX® Lotion, 0.05%. syndrome, Conditions which increase systemic absorption include the
mineral oil, polyoxyethylene glycol 300 isostearate, carbomer 1342, sodium
localized lesions (less than 10% Patients should be instructed to use CLOBEX® (clobetasol
children.HPA axis suppression, Cushing's syndrome, linear growth
They are metabolized, primarily in the liver, and The mechanism
They may occur more frequently with the use of
treated with vehicle achieved success. or very mild (no or very slight clinical signs or symptoms of erythema,
65 and over to determine whether they respond differently than younger
CLOBEX® (clobetasol
receiving topical corticosteroids. 0.05% should not be used with occlusive dressings.Store at controlled room temperature 68° to 77°F
Therefore, patients
If no Allergic contact
numerically high rates of HPA axis suppression (See 2 fl. These doses are approximately 0.14 to 1.4 times, CLOBEX ® (clobetasol propionate) Lotion, 0.05% is a super-high potent corticosteroid formulation indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses only in patients 18 years of age or older (see PRECAUTIONS).Treatment should be limited to 2 consecutive weeks. greater frequency of decreased hepatic, renal or cardiac function, and of
illness or injury may have increased morbidity and mortality with intermittent It may harm
HPA axis suppression. skin, topical corticosteroids are handled through pharmacokinetic pathways
discontinued from the study for reasons related to the safety or tolerability
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