These side effects may go away during treatment as your body adjusts to the medicine. 2003;80 Suppl 1:S3-11; discussion S13-8. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. I am cancer free since my surgery and the pills and hope to remain so. Springer All rights reserved. In the ATAC trial, no statistically significant differences in weight gain between anastrozole and tamoxifen were found after 12 months of follow-up [+1.4 kg (SD 3.9) vs. +1.5 kg (SD 4.0), P = 0.4]. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Get emergency help immediately if any of the following symptoms of overdose occur:Some side effects may occur that usually do not need medical attention. 2018 Dec 1;124(23):4512-4519. doi: 10.1002/cncr.31775. Generally, weight gain … Please enable it to take advantage of the complete set of features! 1. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Both drugs seem close in their side effects…just the more serious ones … 2008 Oct;9(10):953-61. doi: 10.1016/S1470-2045(08)70207-9. Too many joint aches, hot/cold flushes, muscle cramps, tingling fingers, etc. Name must be less than 100 characters Weight gain with Arimidex occurs in up to 9 percent of people taking the drug. 2018 Feb;18(1):e7-e13. Epub 2008 Sep 1.Clin Breast Cancer. All drugs may cause side effects.
Data on weight change in postmenopausal women from three large clinical trials investigating endocrine therapy for the treatment or prevention of breast cancer were analysed (ATAC, IBIS-I and IBIS-II). In the prevention trials, weight gain does not differ between anastrozole, tamoxifen and placebo and also did not differ between anastrozole and tamoxifen in the treatment trial. 2016 Jun 1;18(1):58. doi: 10.1186/s13058-016-0713-5. Breast Cancer Res Treat. doi: 10.3816/cbc.2003.s.014.Anderson C, Nichols HB, Deal AM, Park YM, Sandler DP.Cancer. 2017 Nov 9;377(19):1836-1846. doi: 10.1056/NEJMoa1701830.Simigdala N, Gao Q, Pancholi S, Roberg-Larsen H, Zvelebil M, Ribas R, Folkerd E, Thompson A, Bhamra A, Dowsett M, Martin LA.Breast Cancer Res.
However, it is difficult to tell if this weight gain is caused by Arimidex or by other factors, due to the way clinical studies of Arimidex were designed. Proposed Answer: It is not uncommon for women to gain weight while taking Arimidex. Chest pain or pressure or a fast heartbeat. Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. 2016 Feb 27;387(10021):866-73. doi: 10.1016/S0140-6736(15)01129-0. If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects.
Epub 2015 Dec 11.Margolese RG, Cecchini RS, Julian TB, Ganz PA, Costantino JP, Vallow LA, Albain KS, Whitworth PW, Cianfrocca ME, Brufsky AM, Gross HM, Soori GS, Hopkins JO, Fehrenbacher L, Sturtz K, Wozniak TF, Seay TE, Mamounas EP, Wolmark N.Lancet. Pixie Dust.
Exercise and a good low fat diet are the best strategies to combat the problem. I had gained weight before the medication and took an aggressive stance this past November and have lost 31 … Since weight gain may impact on outcome and compliance we have prospectively assessed the effects of these agents on weight change in three randomised trials for the treatment or prevention of breast can … Weight change associated with anastrozole and … All three trials demonstrate that weight gain occurs primarily within the first 12 months of active treatment in a subset of patients. The amount or weight can be variable. Since weight gain may impact on outcome and compliance we have prospectively assessed the effects of these agents on weight change in three randomised trials for the treatment or prevention of breast cancer. Epub 2018 Oct 6.Raghavendra A, Sinha AK, Valle-Goffin J, Shen Y, Tripathy D, Barcenas CH.Clin Breast Cancer. However, hormone-reducing therapies may cause weight gain in certain subsets of women because they counteract the effects of estrogen, which helps suppress the activity of an enzyme called LPL that pulls fat into cells.
Shortness of breath, a big weight gain, or swelling in the arms or legs. Arimidex and Weight Gain: An Overview Weight gain is a common complaint in people taking Arimidex ® (anastrozole).
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