In addition, doxycycline comes in a solution for injection, which is only given by a healthcare provider.Doxycycline is used to treat bacterial infections. If you log out, you will be required to enter your username and password the next time you visit. Rocky Mountain spotted fever, typhus fever and the typhus group, Q fever, rickettsialpox, and tick fevers caused by RickettsiaeInitial: 200 mg/day divided twice daily PO/IV on first day (IV may be given qDay), THENMaintenance: 100-200 mg/day qDay or divided q12hr PO/IV (IV may be given qDay)Uncomplicated urethral, endocervical or rectal infections caused by Chlamydia trachomatisNongonococcal urethritis caused by Ureaplasma urealyticumLymphogranuloma venereum caused by Chlamydia trachomatisGranuloma inguinale caused by Klebsiella granulomatisUncomplicated gonorrhea caused by Neisseria gonorrhoeaeUncomplicated urethral, endocervical, or rectal infection caused by Chlamydia trachomatis: 100 mg PO BID for 7 daysAlternate dosing regimen for uncomplicated urethral or endocervical infection caused by Chlamydia trachomatis: 200 mg PO BID for 7 daysUncomplicated gonococcal infections (except anorectal infections in men): 100 mg PO BID for 7 daysAlternate single visit dose: 300 mg stat followed in 1 hr by a second 300 mg doseNongonococcal urethritis (NGU) caused by U. urealyticum: 100 mg PO BID for 7 dayRespiratory tract infections caused by Mycoplasma pneumoniaePsittacosis (ornithosis) caused by Chlamydophila psittaciIndicated for respiratory tract infections caused by the following microorganisms, when bacteriological testing indicates appropriate susceptibility to drug: Haemophilus influenzae, Klebsiella species, Streptococcus pneumoniaeInitial: 200 mg/day divided twice daily PO/IV on first day (IV may be given qDay), THENMaintenance: 100-200 mg/day qDay or divided q12hr PO/IV (IV may be given qDay)Campylobacter fetus infections caused by Campylobacter fetusBrucellosis due to Brucella species (in conjunction with streptomycin)Gram negative microorganisms (eg, Escherichia coli Enterobacter aerogenes, Shigella species, Acinetobacter species, urinary tract infections caused by Klebsiella species)Initial: 200 mg/day divided twice daily PO/IV on first day (IV may be given qDay), THENMaintenance: 100-200 mg/day qDay or divided q12hr PO/IV (IV may be given qDay)Trachoma caused by Chlamydia trachomatis, although the infectious agent is not always eliminated as judged by immunofluorescenceInclusion conjunctivitis caused by Chlamydia trachomatisAcute epididymo-orchitis caused by C. trachomatis: 100 mg, PO BID for at least 10 daysAnthrax due to Bacillus anthracis, including inhalational anthrax (postexposure)Adjunctive therapy for acute intestinal amebiasis and severe acneInitial: 200 mg/day divided twice daily PO/IV on first day (IV may be given qDay), THENMaintenance: 100-200 mg/day qDay or divided q12hr PO/IV (IV may be given qDay)Indicated for prophylaxis of malaria due to Plasmodium falciparum in short-term travelers (<4 months) to areas with chloroquine and/or pyrimethamine-sulfadoxine resistant strainsProphylaxis: 100 mg PO qDay; begin taking 1-2 days before travel and continue daily during travel and for 4 weeks after traveler leaves malaria infested areaSevere infection (off-label): 100 mg PO/IV q12hr x 7 days with 3-7 days quinidine gluconateUncomplicated infection (off-label): 100 mg PO q12hr x 7 days with 3-7 days quinine sulfate depending on regionAtridox: Apply subgingivally; dose depends on size, shape, and number of pockets treated≤8 years: Not recommended for mild-to-moderate infections; may cause tooth discoloration and enamel hypoplasia during tooth developmentAnthrax due to Bacillus anthracis, including inhalational anthrax (postexposure)≤8 years: 2.2 mg/kg PO/IV q12hr for 60 days (change to amoxicillin as soon as penicillin susceptibility confirmed) Jarisch-Herxheimer reaction in the setting of spirochete infectionsUse of tetracyclines during tooth development (last half of pregnancy through age 8 years) can cause permanent discoloration of teeth; use doxycycline in pediatric patients 8 years of age or less only when potential benefits expected to outweigh risks in severe or life-threatening conditions (eg, anthrax, Rocky Mountain spotted fever); particularly when there are no alternative therapiesClostridium difficile associated diarrhea (CDAD) has been reported with use of nearly all antibacterial agents, and may range in severity from mild diarrhea to fatal colitisPhotosensitivity manifested by an exaggerated sunburn reaction has been observed in some individuals taking tetracyclinesMay result in overgrowth of non-susceptible organisms, including fungi.
Serious side effects and their symptoms can include the following:Doxycycline oral tablet is a prescription drug that’s available as the brand-name drugs Acticlate, Doryx, and Doryx MPC. Buckingham SC, Marshall GS, Schutze GE, et al.
Archibald LK, Sexton DJ.
Rocky Mountain spotted fever (RMSF), human monocytic ehrlichiosis (HME), human granulocytic anaplasmosis (HGA), and Ehrlichia ewingii infection are the diseases most common in the United States. If you eat or drink these items, do so at least one hour before taking this drug or one hour after taking this drug.Talk to your doctor if you’re pregnant or planning to become pregnant.
Managing Rocky Mountain spotted fever. DuPont HL, Hornick RB, Dawkins AT, et al. Case fatality rate by age-group for spotted fever rickettsioses (including RMSF) in the United States, 2008-2012.
Holman RC, McQuiston JH, Haberling DL, Cheek JE. Diseases & Conditions
A focus of Rocky Mountain spotted fever within New York City.
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