By continuing to browse this site, you agree to its use of cookies as described in our I have read and accept the Wiley Online Library Terms and Conditions of UsePharmacokinetics and safety of S/GSK1349572, a next‐generation HIV integrase inhibitor, in healthy volunteersDolutegravir in antiretroviral‐experienced patients with raltegravir‐ and/or elvitegravir‐resistant HIV‐1: 24‐week results of the phase III VIKING‐3 studyEffect of antacids on the pharmacokinetics of raltegravir in human immunodeficiency virus‐seronegative volunteersPharmacokinetics of the HIV integrase inhibitor S/GSK1349572 co‐administered with acid‐reducing agents and multivitamins in healthy volunteersEffect of food on the pharmacokinetics of the integrase inhibitor dolutegravirPrevalence and outcomes of anemia in individuals with human immunodeficiency virus: a systematic review of the literatureImpact of Therapeutic Drug Monitoring of Antiretroviral Drugs in Routine Clinical Management of People Living With HIV, The challenge of HIV treatment in an era of polypharmacy, Comparing ultrafiltration and equilibrium dialysis to measure unbound plasma dolutegravir concentrations based on a design of experiment approach, Interactions between antiretroviral therapy and complementary and alternative medicine: A narrative review, Concurrent administration with multivalent metal cation preparations or polycationic polymer preparations inhibits the absorption of raltegravir via its chelation, Drug–Drug Interactions with Antiretroviral Drugs in Pregnant Women Living with HIV: Are They Different from Non-Pregnant Individuals?, HIV-1 Virologic Rebound Due to Coadministration of Divalent Cations and Bictegravir, The antagonism of folate receptor by dolutegravir, Mechanistic Assessment of Extrahepatic Contributions to Glucuronidation of Integrase Strand Transfer Inhibitors, Nutrition Habits in People Living with HIV/AIDS in Bulgaria: Review of Current Practice and Recommendations, Nutrition and HIV/AIDS - Implication for Treatment, Prevention and Cure [Working Title], HIV Viral Rebound Due to a Possible Drug–Drug Interaction between Elvitegravir/Cobicistat/Emtricitabine/Tenofovir Alafenamide and Calcium-Containing Products: Report of 2 Cases, Journal of the International Association of Providers of AIDS Care (JIAPAC), Dolutegravir Population Pharmacokinetics in a Real-Life Cohort of People Living With HIV Infection, Prescribing issues in elderly individuals living with HIV, Canadian guideline on HIV preexposure prophylaxis and nonoccupational postexposure prophylaxis for pharmacists, Canadian Pharmacists Journal / Revue des Pharmaciens du Canada, Drug–drug interactions of a two-drug regimen of dolutegravir and lamivudine for HIV treatment, Pharmacokinetic drug evaluation of ritonavir (versus cobicistat) as adjunctive therapy in the treatment of HIV, Effects of Low- and High-Mineral Content Water on the Relative Bioavailability of a Coformulated Abacavir/Dolutegravir/Lamivudine Dispersible Tablet in Healthy Adults, JAIDS Journal of Acquired Immune Deficiency Syndromes, Drug interactions with carbamazepine: An ever expanding list?, Crushing of dolutegravir fixed-dose combination tablets increases dolutegravir exposure, Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions, Mechanisms of Drug Interactions I: Absorption, Metabolism, and Excretion, Drug Interactions in Infectious Diseases: Mechanisms and Models of Drug Interactions, Dolutegravir plus rilpivirine dual therapy in treating HIV-1 infection, A review of drug-drug interactions in older HIV-infected patients, Dolutegravir plasma levels after gastric bypass surgery, Relative Bioavailability of a Dolutegravir Dispersible Tablet and the Effects of Low‐ and High‐Mineral‐Content Water on the Tablet in Healthy Adults, Effects of ritonavir and cobicistat on dolutegravir exposure: when the booster can make the difference, Dietary supplement interactions with antiretrovirals: a systematic review, Drug interactions in HIV treatment: complementary & alternative medicines and over-the-counter products, Strengths, weaknesses, opportunities and challenges for long acting injectable therapies: Insights for applications in HIV therapy, Substantially lowered dolutegravir exposure in a treatment-experienced perinatally HIV-1-infected pregnant woman, Dolutegravir as maintenance monotherapy: first experiences in HIV-1 patients: Table 1., Dual antiviral therapy for HIV and hepatitis C – drug interactions and side effects,
Home; Byggservice; Nybyggnation; FAQs; Om oss Rau O, Wurglics M, Dingermann T, Abdel-Tawab M, Schubert-Zsilavecz M. Screening of herbal extracts for activation of the human peroxisome proliferator-activated receptor. Publications. While subjects are taking calcium/iron supplements, a separation strategy for dosing under fasted conditions is warranted, similar to the dosing recommendations for metal cation‐containing antacids.Another strategy to counteract the interaction was to give the dolutegravir and the mineral supplement concomitantly with a meal, because food increases the exposure of dolutegravirThis study demonstrates that dolutegravir was well tolerated when given with calcium or iron supplements.
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