Therefore, it should be borne in mind that the dangers inherent in a suicide attempt or accidental overdosage with the drug may be increased for the patient who uses excessive amounts of alcohol.
Strikethrough Discontinued. Continue to take imipramine even if you feel well. That means you may need to take it with other medications.Imipramine oral tablet is used to treat symptoms of Imipramine works on your central nervous system to increase the levels of certain chemicals in your brain. Version: 12.01.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. When imipramine tablets are used to prevent bedwetting in children, they are usually taken one hour before bedtime. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Available in:Store at 20°C to 25°C (68° to 77°F) [See USP Controlled Room Temperature].Depending on the dosage in both species, toxic signs proceeded progressively from depression, irregular respiration and ataxia to convulsions and death.Oral: Independent studies in three species (rat, mouse, and rabbit) revealed that when Imipramine hydrochloride is administered orally in doses up to approximately 2-1/2 times the maximum human dose in the first 2 species and up to 25 times the maximum human dose in the third species, the drug is essentially free from teratogenic potential. You may report side effects to FDA at 1-800- FDA-1088.This Medication Guide has been approved by the U.S. Food and Drug Administration for all antidepressants.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Imipramine can make you sunburn more easily. You also can obtain the Medication Guide from the FDA website: No matter your age, before you take an antidepressant, you, your parent, or your caregiver should talk to your doctor about the risks and benefits of treating your condition with an antidepressant or with other treatments. Overdose symptoms may include irregular heartbeats, feeling like you might pass out, seizures, or coma.Avoid driving or hazardous activity until you know how imipramine will affect you. You should know that having depression or another mental illness greatly increases the risk that you will become suicidal. The drugs that inhibit cytochrome P450 2D6 include some that are not metabolized by the enzyme (quinidine; cimetidine) and many that are substrates for P450 2D6 (many other antidepressants, phenothiazines, and the Type 1C antiarrhythmics propafenone and flecainide). Pre-existing glaucoma is almost always open-angle glaucoma because angle-closure glaucoma, when diagnosed, can be treated definitively with iridectomy. The risk differences (drug vs. placebo), however, were relatively stable within age strata and across indications.
The plasma concentration of imipramine may increase when the drug is given concomitantly with hepatic enzyme inhibitors (e.g., cimetidine, fluoxetine) and decrease by concomitant administration with hepatic enzyme inducers (e.g., barbiturates, phenytoin), and adjustment of the dosage of imipramine may therefore be necessary. Imipramine is a prescription drug. Short-term studies did not show an increase in the risk of suicidality with antidepressants compared to placebo in adults beyond age 24; there was a reduction with antidepressants compared to placebo in adults aged 65 and older.The pooled analyses of placebo-controlled trials in children and adolescents with MDD, obsessive compulsive disorder (OCD), or other psychiatric disorders included a total of 24 short-term trials of 9 antidepressant drugs in over 4400 patients. Avoid being in the sun if you can. Imipramine is in a class of medications called tricyclic antidepressants. Be sure to tell your doctor about all medications, vitamins, or herbs you’re taking. However, experts are not sure about how great this risk is and how much it should be considered in deciding whether a child or teenager should take an antidepressant. Imipramine hydrochloride USP, the original tricyclic antidepressant, is a member of the dibenzazepine group of compounds. There is not enough information to explain how imipramine prevents bedwetting.Imipramine comes as a tablet and a capsule to take by mouth.
https://www.webmd.com/drugs/2/drug-8664/imipramine-oral/details
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