Sign in here to access free tools such as favourites and alerts, or to access personal subscriptionsIf you have access to journal content via a university, library or employer, sign in hereResearch off-campus without worrying about access issues. Rodby RA et al. Naimark D et al. Clarke P et al. and JavaScript.There are substantial healthcare costs associated with the provision of renal replacement therapy. Trends in the incidence of renal replacement therapy for end–stage renal disease in Europe, 1990–1999. This site uses cookies.
Irbesartan 150 mg demonstrated comparable efficacy to amlodipine 5 mg, thereby confirming its value as an antihypertensive treatment option in non-African American patients with DBP 95—110 mmHg.Research off-campus without worrying about access issues.
7 (2), 2003.Lamping DL et al. Cost savings with irbesartan treatment instead of amlodipine or standard blood pressure control alone begin to occur after 3–4 years of therapy.The results of this modelling study were robust under a wide range of plausible assumptions about the long-term effectiveness of drug therapy and costs of complications and medications, even in the extreme case assuming no effect of irbesartan or amlodipine after the 3-year trial period. In the unlikely case that the annual costs of dialysis in the UK fell below £3000 (compared to £21 456 used in the base-case analysis and £20 245 identified as the lower limit of the range reported in the literature), irbesartan would no longer be cost saving compared to standard blood pressure control alone. These probabilities were derived from UK-specific ESRD management and outcomes data (A National Health Service (NHS) payer perspective was taken for all the costs used in this simulation. On eHealthMe, you can check real-world data from 16 million patients, and personalize the results to your gender and age. When an adjustment was made for the differences in blood pressure control between the irbesartan and placebo groups, the magnitude of renal benefit afforded by irbesartan did not decrease significantly.Patients included in IDNT had type II diabetes, hypertension and advanced proteinuria, and as such these results should only be taken in this context and not be extrapolated to patients with type II diabetes with less severe renal disease, or to those only with hypertension. Using treatment-specific probabilities derived from the Irbesartan in Diabetic Nephropathy Trial (IDNT), the cost effectiveness of treating patients with hypertension, type II diabetes and nephropathy with irbesartan, amlodipine or control was calculated using a Markov model. An economic evaluation of irbesartan in the treatment of patients with type 2 diabetes, hypertension and nephropathy; cost-effectiveness of Irbesartan in Diabetic Nephropathy Trial (IDNT) in the Belgian, and French settings. Clinical outcomes, quality of life, and costs in the North Thames Dialysis Study of elderly people on dialysis: a prospective cohort study. Treatment leading to a slowing of progression to ESRD in diabetic patients could lead to considerable cost savings. Irbesartan adalah obat penghambat reseptor angiotensin II (ARB) yang digunakan untuk mengatasi tekanan darah tinggi dan nefropati diabetik.Pembuluh darah bisa menyempit akibat pengaruh angiotensin II, dan irbesartan berfungsi menghambat efek tersebut, sehingga melebarkan pembuluh darah dan mengurangi tekanan pada pembuluh darah. Kjeldsen SE et al. Primary Objective: To demonstrate that the antihypertensive efficacy of the fixed combination irbesartan/amlodipine 300/5 mg is superior to that of irbesartan 300 mg monotherapy in lowering systolic blood pressure (SBP) as measured by home blood pressure measurement (HBPM) after 10 weeks of treatment (W10) Secondary Objective: - To compare the antihypertensive efficacy of the fixed … Find out about Lean Library If you have an individual subscription to this content, or if you have purchased this content through Subjects were 18—65 years of age, with DBP 95—110 mmHg, and of non-African American origin. 2012 Aug;34(8):1720-34.e3. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33).
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