Mavyret (glecaprevir / pibrentasvir) drug interactions.
Mavyret glecaprevir 100 mg / pibrentasvir 40 mg (NXT) Interaction Checkers. Prescribers should exercise caution when treating patients previously infected with HBV/HCV.
We comply with the HONcode standard for trustworthy health information - Inform patients that Mavyret may interact with some drugs; therefore, patients should be advised to report to their healthcare provider the use of any prescription, non-prescription medication or herbal products [see Contraindications , Warnings and Precautions and Drug Interactions ]. Prescribing Resources Videos Site News. Mission Statement Editorial Board Meet the Team. Interaction Checker Interaction Checker Lite View All Checker.
No dosage adjustment is required in patients with mild hepatic impairment (Child-Pugh A).Moderate Potential Hazard, Moderate plausibility. Select one or more newsletters to continue. Apps. HEP Drug Interactions. Support Us.
Administration See full prescribing information for MAVYRET. Mavyret Drug Information / Drug Summary email print Close window. The new treatment selector can be found in the prescribing resources section.
Mavyret doesn’t have any reported drug interactions with alcohol use. Select one or more newsletters to continue. Download from Google Play. Screening for current or prior viral hepatitis B/C infection should be performed per published guidelines before starting therapy with this agent. Download from the AppStore. Discontinue Mavyret in patients who develop evidence of hepatic decompensation/failure.Mavyret is contraindicated in patients with moderate to severe hepatic impairment (Child-Pugh B or C) or those with any history of prior hepatic decompensation Overall Adverse Reactions in HCV-Infected Adults without Cirrhosis or with Compensated Cirrhosis (Child-Pugh A)Adverse Reactions in HCV-Infected Adults without Cirrhosis Treated with Mavyret in Controlled TrialsAdverse Reactions in Subjects with Compensated Cirrhosis (Child-Pugh A)Adverse Reactions in HCV-Infected Adults with Severe Renal Impairment Including Subjects on DialysisAdverse Reactions in HCV/HIV-1 Co-infected SubjectsAdverse Reactions in Subjects with Liver or Kidney TransplantAdverse Reactions in People Who Inject Drugs (PWID) and those on Medication-Assisted Treatment (MAT) for Opioid Use DisorderGlecaprevir/Pibrentasvir Film-Coated Immediate Release TabletsStudies in Treatment-Naïve and (peg)Interferon, Ribavirin and/or Sofosbuvir Treatment-Experienced Subjects with or without CirrhosisStudies in Subjects with or without Cirrhosis Who Were Treatment-Experienced to NS3/4A Protease and/or NS5A InhibitorsEffect of Baseline HCV Amino Acid Polymorphisms on Treatment Response (NS3/4A PI- and NS5A Inhibitor-Naïve Subjects)Subjects with CKD Stage 4 and 5 without Cirrhosis or with Compensated CirrhosisNS5A Inhibitor or PI-Experienced Subjects without Cirrhosis or with Compensated CirrhosisHCV/HIV-1 Co-Infected Subjects without Cirrhosis or with Compensated CirrhosisLiver or Kidney Transplant Recipients without CirrhosisAdolescent Subjects (12 years to less than 18 years)Demographics and Baseline Characteristics of Clinical Trials in Treatment-Naïve or Treatment-Experienced Adults to (peg)Interferon, Ribavirin and/or Sofosbuvir (PRS) without Cirrhosis or with Compensated Cirrhosis (Child-Pugh A)Subjects with Genotype 3b Infection in VOYAGE-1 and VOYAGE-2Risk of Hepatitis B Virus Reactivation in Patients Coinfected with HCV and HBVRisk of Hepatic Decompensation/Failure in Patients with Evidence of Advanced Liver DiseaseWhat is the most important information I should know about Mavyret?For more information about side effects, see the section “What are the possible side effects of Mavyret?”Before taking Mavyret, tell your healthcare provider about all of your medical conditions, including if you:Tell your healthcare provider about all the medicines you takeKeep a list of your medicines to show your healthcare provider and pharmacist.Do not start taking a new medicine without telling your healthcare provider.In people who had or have advanced liver problems before starting treatment with Mavyret: rare risk of worsening liver problems, liver failure and death.Keep Mavyret and all medicines out of the reach of children.General information about the safe and effective use of MavyretDo not accept if seal over bottle opening is broken or missing.We comply with the HONcode standard for trustworthy health information - Feedback Form Suggest a Drug.
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