Mometasone furoate is a synthetic corticosteroid with anti-inflammatory activity.Chemically, mometasone furoate is 9α, 21-dichloro-11β,17-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 17-(2-furoate), with the empirical formula CMometasone furoate is a white to off-white powder insoluble in water, freely soluble in acetone and in methylene chloride and sparingly soluble in heptane.Each gram of Mometasone Furoate Topical Solution USP, 0.1% contains 1 mg mometasone furoate in a colorless, clear to translucent solution base of isopropyl alcohol (40%), hexylene glycol, hydroxypropyl cellulose, sodium phosphate monobasic anhydrous, purified water, glycerin and oleic acid. Do not apply Mometasone Furoate Topical Solution, 0.1% in the diaper area if the patient requires diapers or plastic pants, as these garments constitute occlusive dressing.Mometasone Furoate Topical Solution 0.1% is for topical use only. Postmarketing reports for local adverse reactions to topical corticosteroids include irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, secondary infection, skin atrophy, striae, and malaria. Prolonged use may affect growth velocity; growth should be routinely monitored in pediatric patients.• Appropriate use: Avoid use of topical preparations with occlusive dressings or on weeping or exudative lesions.Adrenal suppression with extensive/prolonged use (ACTH stimulation test, morning plasma cortisol test, urinary free cortisol test); response to treatment; ocular changesAdverse events have been observed in animal reproduction studies.Systemic bioavailability of topical corticosteroids is variable (integrity of skin, use of occlusion, etc.) Warnings and Precautions (5.1) and Use in Specific Populations (8.4)Mometasone Furoate (moe-MET-a-sone fur-oate) Topical Solution USP, 0.1%Important information: Mometasone Furoate Topical Solution, 0.1% is for use on skin only.Do not use Mometasone Furoate Topical Solution, 0.1% if youBefore using Mometasone Furoate Topical Solution, 0.1%, tell your healthcare provider about all your medical conditions, including if you:Tell your healthcare provider about all the medicines you takeHow should I use Mometasone Furoate Topical Solution, 0.1%?What are the possible side effects of Mometasone Furoate Topical Solution, 0.1%?Mometasone Furoate Topical Solution, 0.1% may cause serious side effects, including:Mometasone Furoate Topical Solution, 0.1% can pass through your skinThe most common side effects of Mometasone Furoate Topical Solution, 0.1% includeHow should I store Mometasone Furoate Topical Solution, 0.1%?Keep Mometasone Furoate Topical Solution, 0.1% and all medicines out of the reach of childrenGeneral information about the safe and effective use of Mometasone Furoate Topical Solution, 0.1%.What are the ingredients in Mometasone Furoate Topical Solution, 0.1%? We comply with the HONcode standard for trustworthy health information - You may report side effects to FDA at 1-800-FDA-1088.Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. Manifestations of Cushing's syndrome, hyperglycemia, and glucosuria can also be produced in some patients by systemic absorption of topical corticosteroids while on treatment. Mometasone furoate nasal spray (MFNS) is a INCS that is used in the management of CRS. 17-Heteroaroyl esters of corticosteroids. Shapiro EL, Gentles MJ, Tiberi RL et al. Each gram of Mometasone Furoate Topical Solution USP, 0.1% contains 1 mg of mometasone furoate in a colorless, clear to translucent solution base.Mometasone Furoate Topical Solution, 0.1% is contraindicated in those patients with a history of hypersensitivity to any of the components in the preparation.Systemic absorption of topical corticosteroids can produce reversible hypothalamic-pituitary-adrenal (HPA) axis suppression with the potential for glucocorticosteroid insufficiency. Fetal survival was reduced at 180 mcg/kg.
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