2010
Higher daily doses may be required and the dose should be adjusted individually. Select one or more newsletters to continue.
By intravenous infusion. Doxycycline may be an effective alternative.Above 8 years of age: 25 to 50 mg/kg orally per day divided in 4 equal dosesTotal dosage should be decreased by reduction of recommended individual doses and/or by extending time intervals between doses.Tetracycline may induce photosensitivity in some individuals.
Adult & Pediatric Dosages: Tablet: Schedule IV. Doxycycline may be an effective alternative.Although tetracyclines in general may be useful in combination with other agents for the treatment of pelvic inflammatory disease, doxycycline is much more commonly used and is specifically recommended by the CDC as a therapy for this disease.
250mg; 500mg; Chronic Bronchitis, Acute Exacerbation . Follow your doctor's orders or the directions on the label.
20 mg once daily, increased if necessary to 40 mg once daily, in severe ulcerating reflux oesophagitis, maximum 12 weeks at higher dose.
Adult Pediatric. Select one or more newsletters to continue.
Usual daily dose: 500 mg PO q12hr or 250 mg PO q6hr (ie, 1000 mg/day) Higher doses (eg, 500 mg PO q6hr) may be required for severe infections or for those infections which do not respond to the smaller doses.
Capsule, delayed release. Safety and efficacy of omeprazole for maintenance treatment past 1 year not establishedVarious regimens exist of PPIs combined with antibiotics, an example is listed below60 mg PO qDay (initial) up to 360 mg/day divided q8hr PO Hepatic impairment: Not studied; expert analysis recommends a reduction in dose, especially for maintenance of healing of erosive esophagitisIndicated for treatment and to maintain healing of erosive esophagitis caused by acid-mediated GERDRefractory duodenal ulcer or reflux esophagitis: 0.5-1.5 mg/kg PO qDay for up to 8 weeks Hypersensitivity to omeprazole or other proton pump inhibitors (PPIs)PPIs are possibly associated with increased incidence of Clostridium difficile-associated diarrhea (CDAD); consider diagnosis of CDAD for patients taking PPIs who have diarrhea that does not improveCutaneous lupus erythematosus (CLE) and systemic lupus erythematosus (SLE) reported with PPIs; avoid using for longer than medically indicated; discontinue if signs or symptoms consistent with CLE or SLE are observed and refer patient to specialistShown to cause gastric carcinoid tumors in rats with increased doses, but risk in humans unconfirmedPublished observational studies suggest that PPI therapy may be associated with an increased risk for osteoporosis-related fractures of the hip, wrist, or spine, particularly with prolonged (>1 yr), high-dose therapyHypomagnesemia may occur with prolonged use (>1 year); adverse effects may result and include tetany, arrhythmias, and seizures; in 25% of cases reviewed, magnesium supplementation alone did not improve low serum magnesium levels and the PPI had to be discontinuedDecreased gastric acidity increases serum chromogranin A (CgA) levels and may cause false-positive diagnostic results for neuroendocrine tumors; temporarily discontinue PPIs before assessing CgA levelsInhibits hepatic isoenzyme CYP2C19 and may alter metabolism of drugs that are CYP2C19 substratesPPIs may decrease the efficacy of clopidogrel by reducing the formation of the active metaboliteStop use and inform a healthcare professional if rash or joint pain developsDaily long-term use (e.g., longer than 3 years) may lead to malabsorption or a deficiency of cyanocobalaminAcute interstitial nephritis has been observed in patients taking PPIsRelief of symptoms does not eliminate the possibility of a gastric malignancyTherapy increases risk of Salmonella, Campylobacter, and other infectionsMay elevate and/or prolong serum concentrations of methotrexate and/or its metabolite when administered oncomitantly with PPIs, possibly leading to toxicity; consider a temporary withdrawal of PPI therapy therapy with high dose methotrexate administrationPPI therapy is associated with increased risk of fundic gland polyp; risk increases with long-term use >1 year; patient may be asymptomatic; problem usually identified incidentally on endoscopy; use shortest duration of therapy appropriate to condition being treatedIf patient taking a prescription drug, the patient should ask a doctor or a pharmacist whether acid reducers can be taken concomitantly with itThere are no adequate and well-controlled studies in pregnant women; available epidemiologic data fail to demonstrate an increased risk of major congenital malformations or other adverse pregnancy outcomes with first trimester omeprazole use; reproduction studies in rats and rabbits resulted in dose-dependent embryo-lethality at omeprazole doses that were approximately 3.4 to 34 times an oral human dose of 40 mg (based on a body surface area for a 60 kg person)Teratogenicity was not observed in animal reproduction studies with administration of oral esomeprazole (an enantiomer of omeprazole) magnesium in rats and rabbits during organogenesis with doses about 68 times and 42 times, respectively, an oral human dose of 40 mg esomeprazole or 40 mg omeprazole (based on body surface area for a 60 kg person); changes in bone morphology were observed in offspring of rats dosed through most of pregnancy and lactation at doses equal to or greater than approximately 34 times an oral human dose of 40 mg esomeprazole or 40 mg omeprazole; when maternal administration was confined to gestation only, there were no effects on bone physeal morphology in offspring at any ageLimited data suggest omeprazole may be present in human milk; there are no clinical data on effects of omeprazole on breastfed infant or on milk production; developmental and health benefits of breastfeeding should be considered along with mother's clinical need for therapy and any potential adverse effects on breastfed infant from treatment or from underlying maternal conditionA: Generally acceptable.
181753-overview
Dose: 20 mg PO bid x10-14 days; Info: part of multi-drug regimen, dosing may vary; see H. pylori Tx Regimens in Adults guideline; give omeprazole 20 mg PO qd for additional 18 days if ulcer present; give before meals; may open cap, see PPI Administration Alternatives table; do …
Controlled studies in pregnant women show no evidence of fetal risk.Inhibits bacterial protein synthesis by binding with 30S and possibly 50S ribosomal subunit(s)Small amount appears in bile; relative diffusion from blood into CSF: good only with inflammation (exceeds usual MICs) CSF: blood level ratio: inflamed meninges: 25%Half-life: 8-11 hr (normal renal function); 57-108 hr (end-stage renal disease)Excretion: Urine (60% as unchanged drug); feces (as active form)Administer with adequate amounts of fluid with the capsule formulation to wash down the drug and reduce the risk of esophageal irritation and ulcerationAbsorption of tetracycline is impaired by antacids containing aluminum, calcium or magnesium and preparations containing iron, zinc or sodium bicarbonateFood and some dairy products also interfere with absorptionAdding plans allows you to compare formulary status to other drugs in the same class.To view formulary information first create a list of plans.
No toxic adverse effects were detected, and there was no clinically significant bleeding.
1893617-overview
Dosage – Adult: 40 mg once daily to be administered over 20 to 30 minutes.
Omeprazole is a proton pump inhibitor, acting selectively on the gastric parietal cell H + K +-adenosine triphosphatase.Data on the intravenous route are limited in children and not available in infants.. Duration – Change to oral treatment as soon as the patient can eat. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. This study was designed to determine the pharmacokinetics and the optimal dosage of intravenous omeprazole in patients younger than 30 months of age.
-Weight 10 to less than 20 kg: 10 mg orally once a day.
Pediatric dose for GI Qx Rx: สำหรับเด็กน้ำหนัก 10 kg ยาแก้ปวดท้อง Buscopan syr: Ped 10 kg = 3-5ml oral tid pc (3-5 mg/dose) Buscopan iv : Ped 10 kg = 5 mg iv ยาแก้อาเจียน
metronidazole-tetracycline-bismuth-subsalicylate-999479
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