This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.Things to remember when you fill your prescription.WebMD does not provide medical advice, diagnosis or treatment.This survey is being conducted by the WebMD marketing sciences department.All information will be used in a manner consistent with the WebMD Other reported clinical experience has not identified differences in responses between the elderly and younger patients.
The dosage is customarily expressed in terms of the base.Primaquine phosphate is an 8-amino-quinoline compound which eliminates tissue (exoerythrocytic) infection. Primaquine phosphate is 8-[(4-Amino-1-methylbutyl)-amino]-6- methoxyquinoline phosphate, a synthetic compound with potent antimalarial activity. ALBENZA is indicated for the treatment of cystic hydatid disease of the liver, lung, and peritoneum, caused by the larval form of the dog tapeworm, Echinococcus granulosus. Adequate medical support to manage hemolytic risk should be available.Discontinue the use of Primaquine phosphate promptly if signs suggestive of hemolytic anemia occur (darkening of the urine, marked fall of hemoglobin or erythrocytic count).Hemolytic reactions (moderate to severe) may occur in individuals with G6PD deficiency and in individuals with a family or personal history of favism. Acute hemolysis occurs, but patients recover completely if the dosage is discontinued.Primaquine phosphate is recommended only for the radical cure of vivax malaria, the prevention of relapse in vivax malaria, or following the termination of chloroquine phosphate suppressive therapy in an area where vivax malaria is endemic.
Primaquine Phosphate USP Tablets are solid oral formulation round tablet debossed “BY4” available in 26.3 mg and 100 count. The dosage is customarily expressed in terms of the base.Inactive Ingredients: Hypromellose, Lactose Monohydrate, Magnesium Stearate, Microcry…
Take your next dose at the regular time. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac function, and of concomitant disease or other drug therapy.Symptoms of overdosage of Primaquine phosphate include abdominal cramps, vomiting, burning epigastric distress, central nervous system and cardiovascular disturbances, including cardiac arrhythmia and QT interval prolongation, cyanosis, methemoglobinemia, moderate leukocytosis or leukopenia, and anemia.
The use of effective contraception is recommended during treatment and after the end of treatment as follows: Advise sexually-active females of child bearing potential to use effective contraception (methods that result in less than 1% pregnancy rates) when using Primaquine and after stopping treatment until completion of an on-going ovulatory cycle (e.g., up to next menses).
Each tablet contains 26.3 mg of Primaquine phosphate (equivalent to 15 mg of Primaquine base). In studies in rats, teratogenic effects on fetus were observed (see Caution is advised if Primaquine is used concomitantly with other drugs that prolong the QT interval (see Clinical studies of Primaquine did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. https://www.webmd.com/drugs/2/drug-12232/primaquine-oral/details
If you notice other effects not listed above, contact your doctor or pharmacist.Call your doctor for medical advice about side effects. Primaquine phosphate should be administered concurrently in order to eradicate the exoerythrocytic parasites in a dosage of 1 tablet (equivalent to 15 mg base) daily for 14 days. Primaquine phosphate is 8-[(4-Amino-1-methylbutyl)-amino]-6- methoxyquinoline phosphate, a synthetic compound with potent antimalarial activity.
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