Inform patients to discard ProAir Respiclick when the dose counter displays 0 or after the expiration date on the product, whichever comes first.Inform patients that ProAir Respiclick can produce paradoxical bronchospasm. As with all sympathomimetic medications, cardiac arrest and even death may be associated with abuse of ProAir Respiclick.Treatment consists of discontinuation of ProAir Respiclick together with appropriate symptomatic therapy. Children should use ProAir Respiclick under adult supervision, as instructed by the patient’s physician.United States Patent Nos.
Patients should never try to alter the numbers for the dose counter. 2. ProAir Respiclick (albuterol sulfate) inhalation powder is indicated for the treatment or prevention of bronchospasm in patients 4 years of age and older with reversible obstructive airway disease.ProAir Respiclick is indicated for the prevention of exercise-induced bronchospasm in patients 4 years of age and older.For treatment of acute episodes of bronchospasm or prevention of symptoms associated with bronchospasm, the recommended dosage for adults and children 4 years of age or older is 2 inhalations repeated every 4 to 6 hours. Select one or more newsletters to continue. ProAir RespiClick ® (albuterol sulfate) Inhalation Powder is indicated in patients 4 years of age and older for the treatment or prevention of bronchospasm with reversible obstructive airway disease and for the prevention of exercise-induced bronchospasm.. When you open the cap, a dose of ProAir RespiClick will be activated for delivery of the medicine. If additional adrenergic drugs are to be administered by any route, they should be used with caution to avoid deleterious cardiovascular effects.Beta-adrenergic-receptor blocking agents not only block the pulmonary effect of beta-agonists, such as ProAir Respiclick, but may produce severe bronchospasm in asthmatic patients.
However, under certain circumstances, eg, as prophylaxis after myocardial infarction, there may be no acceptable alternatives to the use of beta-adrenergic-blocking agents in patients with asthma. Using Fewer Asthma Meds May Be Safe Option for Some The effectiveness of ProAir Respiclick in children 4 to 11 years with exercise-induced bronchospasm is extrapolated from clinical trials in patients 12 years of age and older with asthma and exercise-induced bronchospasm, based on data from a single-dose study comparing the bronchodilatory effect of ProAir Respiclick 90 mcg and 180 mcg with placebo in 61 patients with asthma, and data from a 3-week clinical trial in 185 asthmatic children 4 to 11 years of age comparing a dose of 180 mcg albuterol 4 times daily with placebo The safety and effectiveness of ProAir Respiclick in pediatric patients below the age of 4 years have not been established.Clinical studies of ProAir Respiclick did not include sufficient numbers of patients aged 65 and over to determine whether they respond differently from younger patients. Following intravenous administration of racemic albuterol, between 25% and 46% of the (R)-albuterol fraction of the dose was excreted as unchanged (R)-albuterol in the urine.In a 2-year study in Sprague-Dawley rats, albuterol sulfate caused a dose-related increase in the incidence of benign leiomyomas of the mesovarium at and above dietary doses of 2 mg/kg (approximately 15 times and 6 times the maximum recommended daily inhalation dose (MRHDID) for adults and children, respectively, on a mg/mAlbuterol sulfate was not mutagenic in the Ames test or a mutation test in yeast. Nevertheless, it would be prudent to carefully evaluate the serum digoxin levels in patients who are currently receiving digoxin and ProAir Respiclick.ProAir Respiclick should be administered with extreme caution to patients being treated with monoamine oxidase inhibitors or tricyclic antidepressants, or within 2 weeks of discontinuation of such agents, because the action of albuterol on the cardiovascular system may be potentiated. Hypersensitivity reactions including anaphylaxis, angioedema, pruritus, and rash have been reported with the use of therapies containing lactose (lactose is an inactive ingredient in ProAir Respiclick).
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