Rizatriptan benzoate is a serotonin (5-HT)1B/1D receptor agonist (triptan) indicated for the acute treatment of migraine with or without aura in adults and in pediatric patients 6 to 17 years of age • History of ischemic heart disease or coronary artery vasospasm (• Myocardial ischemia, myocardial infarction, and Prinzmetal's angina: Perform cardiac evaluation in patients with multiple cardiovascular risk factors (The most common adverse reactions in adults were (incidence ≥ 5% and greater than placebo): asthenia/fatigue, somnolence, pain/pressure sensation and dizziness • Pregnancy: Based on animal data, may cause fetal harm See 17 for PATIENT COUNSELING INFORMATION and FDA-approved patient labeling.The recommended starting dose of rizatriptan benzoate tablets is either 5 mg or 10 mg for the acute treatment of migraines in adults.
The incidences of adverse reactions were not affected by age or gender. Because the reports cite events reported spontaneously from worldwide postmarketing experience, frequency of events and the role of The dose of rizatriptan benzoate should be adjusted in propranolol-treated patients, as propranolol has been shown to increase the plasma AUC of rizatriptan by 70% Ergot-containing drugs have been reported to cause prolonged vasospastic reactions. 33342-088-50, Subarachnoid Hemorrhage (Orphan) New dosage form . Container Type.
33342-088-72
Additional analgesics and/or antiemetics were allowed 2 hours after initial treatment for rescue in all four studies.Comparisons of drug performance based upon results obtained in different clinical trials may not be reliable. Unless otherwise prescribed, the oral dose is 60 mg (two 30 mg capsules) every 4 hours for 21 consecutive days. This information does not take the place of talking to your doctor about your medical condition or your treatment.Rizatriptan benzoate tablet is a prescription medicine that belongs to a class of medicines called Triptans. Gastrointestinal decontamination, (i.e., gastric lavage followed by activated charcoal) should be considered in patients suspected of an overdose with rizatriptan benzoate. Active Ingredient.
33342-088-46, Adverse reaction frequencies were also unchanged by concomitant use of drugs commonly taken for migraine prophylaxis (including propranolol), oral contraceptives, or analgesics.
Because cardiac ischemia can occur in the absence of clinical symptoms, consideration should be given to obtaining on the first occasion of use an electrocardiogram (ECG) during the interval immediately following MAXALT ®, in these … The recommended dose of rizatriptan benzoate tablets is 5 mg in patients weighing less than 40 kg (88 lb), and 10 mg in patients weighing 40 kg (88 lb) or more. The efficacy and safety of riztriptan benzoate tablets in the acute treatment of migraine in patients aged 6 to 17 years was established in an adequate and well-controlled study [Clinical studies of rizatriptan benzoate did not include sufficient numbers of subjects aged 65 and over to determine whether they respond differently from younger subjects. Renal impairment: Supplemental dose not necessary in hemodialysis or peritoneal dialysis. /viewarticle/935751 Sixty-one percent of the patients were Caucasian, and fifty-six percent of the patients were female.
Controlled studies in pregnant women show no evidence of fetal risk.Selective 5-HT1 receptor agonist in cranial arteries; causes vasoconstriction and reduces inflammation associated with antidromic neuronal transmission linked to relief of migraineTablets or ODT: Store at room temperature 15-30ºC (59-86ºF)Adding plans allows you to compare formulary status to other drugs in the same class.To view formulary information first create a list of plans. 33342-088-07, Rizatriptan benzoate tablets, USP should not be prescribed to propranolol-treated pediatric patients who weigh less than 40 kg (88 lb) Rizatriptan benzoate tablets, USP are contraindicated in patients with:Rizatriptan benzoate tablets, USP should not be given to patients with ischemic or vasospastic coronary artery disease.
71335-1577-3, Events are further classified within system organ class and enumerated in order of decreasing frequency using the following definitions: frequent adverse events are those occurring in (>)1/100 pediatric patients; infrequent adverse experiences are those occurring in 1/100 to 1/1000 pediatric patients; and rare adverse experiences are those occurring in fewer than 1/1000 patients.The following section enumerates potentially important adverse events that have occurred in clinical practice and which have been reported spontaneously to various surveillance systems.
33342-087-12,
10mg.
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