It is important that patients start to breathe in as slowly as possible just before operating their inhaler. Seroflo (Salmeterol and Fluticasone) is given to patients suffering from asthma to help prevent asthma attacks. The study was not designed to assess the impact of concurrent inhaled corticosteroid use, and only 47% of subjects reported ICS use at baseline.Two multi-centre 26-week studies were conducted to compare the safety and efficacy of salmeterol-FP versus FP alone, one in adult and adolescent subjects (AUSTRI trial), and the other in paediatric subjects 4-11 years of age (VESTRI trial). Animal studies with salmeterol have shown embryofetal toxicity only at high exposure levels. Despite the seriousness of the c...Asthma is mainly categorized into Mild intermittent asthma,moderate persistent asthma and sever persistent asthma. Although there were no significant differences in the primary endpoint of the combined number of respiratory-related deaths and respiratory-related life-threatening experiences, the study showed a significant increase in asthma-related deaths in patients receiving salmeterol (13 deaths out of 13,176 patients treated with salmeterol versus 3 deaths out of 13,179 patients on placebo). Taking more medication will not improve the symptoms; rather they may cause poisoning or serious side-effects. Pressurized metered dose inhalers (pMDIs), first introduced in 1956, are considered an effective delivery method for many important drugs used to treat asthma and chronic obstructive pulmonary disease (COPD). Following chronic administration of an inhaled dose of 42 mcg of salmeterol inhalation aerosol twice daily, salmeterol was detected in plasma within 5 to 10 minutes in 6 subjects with asthma; plasma concentrations were very low, with mean peak concentrations of 150 pg/mL at 20 minutes and no accumulation with repeated doses. The clinical relevance of these findings is unknown.Fluticasone propionate is a white powder with a molecular weight of 500.6, and the empirical formula is CSalmeterol xinafoate is a white powder with a molecular weight of 603.8, and the empirical formula is CEach sales pack is available as canister containing 120 metered doses and a prescribing information.The canister is pressurized and must be kept away from direct sunlight.The canister must not be punctured, broken or incinerated even when apparently empty.Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Sereflo is not recommended for use in children and adolescents under 18 years of age.Use of a lower strength of this fixed-dose combination can only be obtained by downward dose titration to the lowest strength of this fixed dose combination (containing 50 micrograms of fluticasone propionate). Replace the mouthpiece cover in the correct orientation. What are the side effects of Seroflo 250 Inhaler ? These side-effects have been observed and not necessarily occur.
Children and adolescents <16 years taking high doses of fluticasone propionate (typically ≥ 1000 micrograms/day) may be at particular risk of systemic effects. But I need to know...Continue with the seroflo. Cipla (EU) limited, Dixcart House, Addlestone Road, Bourne Business Park, Addlestone, Surrey, KT15 2LE, United KingdomDixcart House, Addlestone Road, Bourne Business Park, Addlestone,, KT15 2LE, UKTo bookmark a medicine you must sign up and log in.To view the changes to a medicine you must sign up and log in. If salmeterol and fluticasone propionate as a fixed dose combination therapy has to be withdrawn due to overdose of the β agonist component of the drug, provision of appropriate replacement steroid therapy should be considered. These effects are much less likely to occur than with oral corticosteroids. Do not use Currently there are no topics under this specialityCurrently there are no topics under this speciality
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