Sumatriptan and Zolmitriptan. Protein binding ranges from 14% to 21%. Sumatriptan also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms.. Imitrex is available as oral tablets, a nasal spray, and as an injection. Never use this combination of drugs because of high risk for dangerous interactionPotential for serious interaction; regular monitoring by your doctor required or alternate medication may be neededPotential for significant interaction (monitoring by your doctor is likely required)Copyright © 2020 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Other drugs that have the same active ingredients (e.g. Some reports may have incomplete information.Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood.
In the other mesenteric arteries, sumatriptan induced only very weak ( E(max) <5%) or no contraction ( n=13).
Case : A 35-year-old woman presented with severe abdominal pain without diarrhea or hematochezia. We will show you how to give a subcutaneous injection. When the resting tension of the arterial rings was increased moderately by threshold concentrations (EC(10)-EC(20) of maximum contraction induced by 80 mM KCl) with the non-5-HT receptor agonists phenylephrine (10-100 nM), histamine (100 nM-1 microM) or the depolarizing agent KCl (4-10 mM), 5-HT(1B) receptor-mediated responses were amplified in sumatriptan-insensitive arteries (with phenylephrine E(max) 82+/-17%, pD(2) 6.64+/-0.20, n=7; with histamine E(max) 107+/-26%, pD(2) 6.16+/-0.14, n=6; with KCl E(max) 78+/-16%, pD(2) 6.45+/-0.15, n=7). Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. Her blood urea nitrogen was 31 mg/dL, and her creatinine was 1.1 mg/dL, consistent with a prerenal azotemia. The study is based on sumatriptan succinate and methylprednisolone acetate (the active ingredients of Sumatriptan and Depo-medrol, respectively), and Sumatriptan and Depo-medrol (the brand names). Sumatriptan is widely distributed throughout the body. brompheniramine-phenylephrine-dm oral brand names and other generic formulations include:. Clipboard, Search History, and several other advanced features are temporarily unavailable. On eHealthMe, you can check real-world data from 16 million patients, and personalize the results to your gender and age. 2017 Aug 20;17(3):194-202. doi: 10.17305/bjbms.2017.2071.Reboredo M, Chang HC, Barbero R, Rodríguez-Ortigosa CM, Pérez-Vizcaíno F, Morán A, García M, Banales JM, Carreño N, Alegre F, Herrero I, Quiroga J, Prieto J, Sangro B.PLoS One. Applies to: diphenhydramine / hydrocodone / phenylephrine and Depakote ER (divalproex sodium) Using HYDROcodone together with divalproex sodium may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Nasal spray. * Approximation only. 2009 Jul;33(7):1384-91. doi: 10.1007/s00268-009-0011-9.Guven A, Tunc T, Topal T, Kul M, Korkmaz A, Gundogdu G, Onguru O, Ozturk H.Surg Today. While previous in-vitro studies have shown that sumatriptan has no or only weak contractile activity in human omental arteries, recent clinical studies suggest that sumatriptan may induce mesenteric ischaemia. Summary: Drug interactions are reported among people who take Sumatriptan succinate and Keppra together. Albatussin Pediatric Drops Oral, Children's Sudafed PE Cough & Cold Oral, Dimetapp Toddlers Decongestant+Cough Oral, PediaCare Children's Cold Oral, Pediacare Multi-Symptom Cold Oral, Safetussin CD Oral, Triaminic Cold & Cough (PE) Oral Epub 2005 Nov 28.Bosn J Basic Med Sci. Case : A 35-year-old woman presented with severe abdominal pain without diarrhea or … The patient's physical and neurological examination, complete blood count, electrolytes, and erythrocyte sedimentation rate were all within normal limits. Potential for significant interaction (monitoring by your doctor is likely required) 2008;38(11):1029-35. doi: 10.1007/s00595-007-3752-9. These results show that sumatriptan induced concentration-dependent contractions in sumatriptan-sensitive mesenteric arteries and that 5-HT(1B) receptors were present and active in these vessels. Sumatriptan is administered orally, subcutaneously, or intranasally.
Sumatriptan can cause myocardial ischaemia and myocardial infarction. Springer Drug side effects: Sumatriptan … sumatriptan oral and phenylephrine-dm oral both increase serotonin levels. Clinical Drug Interactions Source: Medscape from WebMDDisclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider.
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