Tolterodine is a competitive, specific muscarinic receptor antagonist with a selectivity for the urinary bladder over salivary glands in vivo. It is used to treat disorders of the urinary bladder that affect urination. Epub 2008 Jun 17.Gacci M, Novara G, De Nunzio C, Tubaro A, Schiavina R, Brunocilla E, Sebastianelli A, Salvi M, Oelke M, Gravas S, Carini M, Serni S.BMC Urol. 2011 Apr;30(4):568-71. doi: 10.1002/nau.20923. eCollection 2017.Res Rep Urol. COVID-19 is an emerging, rapidly evolving situation. Tolterodine tartrate extended-release capsules are contraindicated in patients with urinary retention, gastric retention, or uncontrolled narrow-angle glaucoma. doi: 10.1097/01.ju.0000181823.33224.a0. doi: 10.1097/01.ju.0000181823.33224.a0. A single trial found tolterodine extended-release 4 mg/day to have improved efficacy for decreasing urge incontinence episodes along with lower frequency of dry mouth vs. immediate-release tolterodine 2 mg bid. Name must be less than 100 characters 2020 Jul 16;9(7):2262. doi: 10.3390/jcm9072262.Allameh F, Basiri A, Razzaghi M, Abedi AR, Fallah-Karkan M, Ghiasy S, Hosseininia SM, Montazeri S.Clin Pharmacol. It works by preventing spasms of the bladder muscle which can help to reduce the episodes of urinary incontinence or reduce the feeling of urgency that bladder spasms can cause. 2007 Mar 21;297(11):1192-3; author reply 1193. doi: 10.1001/jama.297.11.1192-b.JAMA. This site needs JavaScript to work properly. 2007 Mar 21;297(11):1192; author reply 1193. doi: 10.1001/jama.297.11.1192-a.Kaplan SA, Roehrborn CG, Chancellor M, Carlsson M, Bavendam T, Guan Z.BJU Int. Clipboard, Search History, and several other advanced features are temporarily unavailable. Epub 2008 Sep 25.Neurourol Urodyn. 2020 Mar 1;180(3):411-419. doi: 10.1001/jamainternmed.2019.6398.Curr Urol Rep. 2019 Nov 9;20(11):75. doi: 10.1007/s11934-019-0940-2. Unable to load your collection due to an error One of the tolterodine metabolites (5-hydroxymethyl derivative) exhibits a pharmacological profile similar to that of the parent compound. Wolters Kluwer Silverchair Information Systems Unable to load your delegates due to an error 2017 Jan 10;12(1):e0169248. 2012 Jan 18;1:CD005429. Urine coming from the kidneys fills the bladder and causes it to stretch like a balloon. Tolterodine is used to treat overactive bladder with symptoms of urinary frequency, urgency, and incontinence. Tolterodine reduces spasms of the bladder muscles. This site needs JavaScript to work properly. Tolterodine is a medicine used to treat people who have urinary problems such as urinary incontinence or frequency which are caused by an overactive bladder. eCollection 2016.Curr Urol Rep. 2016 Jul;17(7):48. doi: 10.1007/s11934-016-0604-4. Unfortunately, TURP is associated with some discomforts, including postoperative bleeding, urinary retention, transurethral resection syndrome, infection, bladder pain, and urinary storage symptoms (i.e., frequency, urgency, and nocturia with or without urge incontinence), as well as negative impacts on health-related quality of life (QoL) [4,5,6,7]. 2008 May;179(5 Suppl):S82-5. Name must be less than 100 characters 2008 Nov;72(5):1061-7; discussion 1067. doi: 10.1016/j.urology.2008.06.067. Wolters Kluwer Unable to load your delegates due to an error Other side effects include: constipation, dyspepsia, and dizziness. Commonly reported side effects of tolterodine include: xerostomia. Unable to load your collection due to an error Tolterodine 2 mg bid caused less dose reduction, patient withdrawal, and adverse events, especially dry mouth, compared with oxybutynin 5 mg tid. Epub 2020 Apr 8.Curr Urol Rep. 2017 Jan;18(1):1. doi: 10.1007/s11934-017-0649-z.Kim HJ, Sun HY, Choi H, Park JY, Bae JH, Doo SW, Yang WJ, Song YS, Ko YM, Kim JH.PLoS One. doi: 10.1016/j.juro.2008.03.142.J Urol. JAMA. Please enable it to take advantage of the complete set of features! 2007 Mar 21;297(11):1191-2; author reply 1193. doi: 10.1001/jama.297.11.1191-b.JAMA. 2009 Feb;55(2):472-9. doi: 10.1016/j.eururo.2008.06.032. See below for a comprehensive list of adverse effects. 2005 Dec;174(6):2273-5. discussion 2275-6. doi: 10.1097/01.ju.0000181823.33224.a0. 2020 May 27;12:1756287220929486. doi: 10.1177/1756287220929486. 2008 Nov;102(9):1133-9. doi: 10.1111/j.1464-410X.2008.07761.x. 2009 Sep;10(13):2181-94. doi: 10.1517/14656560903167965.Yuan YF, Zhu WX, Liu T, He JQ, Zhou Q, Zhou X, Zhang X, Yang J.Int J Mol Med. 2016 Apr 26;8:51-9. doi: 10.2147/RRU.S63446. Treatment with tolterodine ER in men with BPH and LUTS may be a reasonable therapeutic option as initial therapy or after failed treatment with alpha-blockers. doi: 10.1016/j.juro.2008.03.142.Roehrborn CG, Kaplan SA, Kraus SR, Wang JT, Bavendam T, Guan Z.Urology. eCollection 2020.Ther Adv Urol. Tolterodine Extended Release Attenuates Lower Urinary Tract Symptoms in Men With Benign Prostatic Hyperplasia J Urol. 2014 Oct 27;14:84. doi: 10.1186/1471-2490-14-84.Expert Opin Pharmacother.
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