To be clear I’ve never used this for actual contraceptive purposes (virgin) and it’s been strictly for my horrible cramps and heavy flow, and getting rid of acne was a plus. There were no exclusions on the basis of weight; … I’ve been off it for 5 days and my skin is slowly getting better. Women with a tendency to chloasma should avoid exposure to the sun or ultraviolet radiation while taking Tri-Lo-Sprintec.The following serious adverse reactions with the use of COCs are discussed elsewhere in labeling:Adverse reactions commonly reported by COC users are:Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in clinical practice.The safety of norgestimate and ethinyl estradiol was evaluated in 1,723 subjects who participated in a randomized, partially blinded, multicenter, active-controlled clinical trial of norgestimate and ethinyl estradiol for contraception. “Well my experience for tri-sprintec I’ve been on it for 3 weeks now almost on my second pack I switched from tri-prevem to this ,this bc gives me horrible side effects the first two weeks I was nauseous all the time and having headaches all the time and this bc is stronger because I am now growing a Linea Nigra believe that’s the name but on the good side my period is not heavy I’ve been having unprotected sex and so far so good I other then the side affects it’s good this but I’m on bc for my skin” (Nursing mothers: Not recommended; can decrease milk production. I’m on week 3 and my face is inflamed with huge under the surface bumps on my cheeks. It is important to continue taking your pills on a regular schedule to prevent a pregnancy.Gray pills: anhydrous lactose, black iron oxide, croscarmellose sodium, hypromellose, magnesium stearate, microcrystalline cellulose, polyethylene glycol, polysorbate 80 and titanium dioxide.Light blue pills: anhydrous lactose, croscarmellose sodium, FD&C blue no. Use non-hormonal contraception when you stop taking Tri-Lo-Sprintec.What should I tell my healthcare provider before taking Tri-Lo-Sprintec?Tell your healthcare provider about all the medicines you take,What are the possible serious side effects of Tri-Lo-Sprintec?Like pregnancy, Tri-Lo-Sprintec may cause serious side effects, including blood clots in your lungs, heart attack, or a stroke that may lead to death. EE is extensively bound (>97%) to serum albumin and induces an increase in the serum concentrations of SHBG.NGM is extensively metabolized by first-pass mechanisms in the gastrointestinal tract and/or liver. However, steroid hormones may be poorly metabolized in patients with hepatic impairment. Do not give Tri-Lo-Sprintec to other people, even if they have the same symptoms that you have.This Patient Information summarizes the most important information about Tri-Lo-Sprintec. Due to inconsistencies between the drug labels on DailyMed and the pill images provided by “Growing up I've always had sensitive skin and mild acne. Some drugs or herbal products that may decrease the effectiveness of COCs include phenytoin, barbiturates, carbamazepine, bosentan, felbamate, griseofulvin, oxcarbazepine, rifampicin, topiramate, rifabutin, rufinamide, aprepitant and products containing St. John’s wort. The first few months, her acne did not clear up and in fact, got a bit worse. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure.Consult the labeling of concurrently used drugs to obtain further information about interactions with hormonal contraceptives or the potential for enzyme alterations.No drug-drug interaction studies were conducted with Tri-Lo-Sprintec.Drugs or herbal products that induce certain enzymes, including cytochrome P450 3A4 (CYP3A4), may decrease the plasma concentrations of COCs and potentially diminish the effectiveness of COCs or increase breakthrough bleeding. Use of this product before menarche is not indicated.Tri-Lo-Sprintec has not been studied in postmenopausal women and is not indicated in this population.The pharmacokinetics of Tri-Lo-Sprintec has not been studied in subjects with hepatic impairment.
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