After the addition of modafinil to the drug regimen of a patient stabilized on clozapine, the patient became symptomatic with dizziness, problems with gait, and sinus tachycardia. Not all drug interactions are bad. Minor drug interactions do not usually cause harm or require a change in therapy.
USES: Modafinil decreases extreme sleepiness due to narcolepsy and other sleep disorders such as difficult/irregular breathing during sleep (e.g., obstructive sleep apnea/hypopnea syndrome-OSAHS). Some reports may have incomplete information.Patients can bring a copy of the report to their healthcare provider to ensure that all drug risks and benefits are fully discussed and understood. If you do not receive an email within 10 minutes, your email address may not be registered, Warfarin is predicted to increase the risk of bleeding events when given with aceclofenac.
In order for us to create your customized HealthSavvy programs, we need a little more information about the health topic(s) that you are interested in. When certain psychotropics are started or discontinued in patients receiving warfarin therapy, or when warfarin is introduced to a patient receiving a stable dose of a psychotropic, clinicians should monitor a patient's international normalized ratio (INR) closely to ensure it remains within therapeutic range. Psychotropics that pose a particular risk of increasing the INR when used with warfarin include fluoxetine, fluvoxamine, quetiapine, and valproic acid. Frazer, PA: Cephalon, Inc.;2007 August.Lexi-Interact [computer program]. An interaction between modafinil and clozapine has been reported in a case report that resulted in clinical side effects. Information on drug interactions with warfarin from the anticoagulation clinic at UC San Diego Health. Drug interactions are reported among people who take Provigil and Coumadin together. Severity of interaction: Severe Evidence for interaction: Theoretical. In order for us to best serve you and provide you with the best information, can you please tell us if you currently have health insurance? On eHealthMe, you can check real-world data from 16 million patients, and personalize the results to your gender and age. ... Drug Interactions Drug/Drug Class Effect on INR Recommendations/Comments; Acetaminophen/APAP ↑ with higher doses: Limit APAP to 2000mg/day: Alcohol ↑ with binging ↓ with chronic use.
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Does Provigil Interact with other Medications? Medications that may cause negative Provigil drug interactions include warfarin, cyclosporine, and diazepam. Drug interactions can also contribute to the cost of healthcare, as a serious drug interaction could result in injury, hospitalization, or rarely, death. Severe Interactions. It also is a drug that binds strongly to plasma albumin and has a short half-life. eMedTV serves only as an informational resource. Boston University Medical Center, Boston, MassachusettsBoston University Medical Center, Boston, MassachusettsBoston University School of Medicine, Boston, MassachusettsBoston University School of Medicine, Boston, MassachusettsBoston University Medical Center, Boston, MassachusettsBoston University Medical Center, Boston, MassachusettsBoston University School of Medicine, Boston, MassachusettsBoston University School of Medicine, Boston, MassachusettsUse the link below to share a full-text version of this article with your friends and colleagues.
© 2020 American College of Clinical Pharmacy BRAND NAME(S): Provigil. These medications are not usually taken together.
Among the drugs that interact with warfarin and decrease the INR, trazodone is the most widely prescribed, with a frequency of 2.2% of the patients who use the anticoagulant, and at least one drug that interacts with it (2). St Louis MO: Wolters Kluwer, 2010 B. Hansten P,Horn J. Interaction Provigil Zoloft All generic drug interactions for sertraline oral (lists will include brand and generic names): 9 contraindicated drug interactions;. Use of this site constitutes acceptance of eHealthMe.com's terms of service and privacy policy. In order for us to best serve you and provide you with the best information, can you please tell us if you currently have health insurance? Frazer, PA: Cephalon, Inc.;2007 August.Lexi-Interact [computer program]. Because warfarin undergoes hepatic metabolism and is highly protein bound, it is particularly prone to drug interactions; in addition, its relatively narrow therapeutic window places patients at risk of either hemorrhagic or thrombotic complications. For clinical details see professional interaction data. A search of the MEDLINE database was performed, and reports of warfarin interactions with psychotropics were identified. * Approximation only. Because warfarin undergoes hepatic metabolism and is highly protein bound, it is particularly prone to drug interactions; in addition, its relatively narrow therapeutic window places patients at risk of either hemorrhagic or thrombotic complications.
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