The BIG 1-98 study was designed to see which hormonal therapy treatment was most effective:
I went to my GP to ask if I could change Brands, but she said it will make no difference and has ordered a blood test, she is then going to contact my oncologist. Tamoxifen may cause hot flashes and increase the risk of blood clots and stroke.
For more information, visit the Breastcancer.org pages on Tamoxifen is the oldest and most-prescribed selective estrogen receptor modulator (SERM)....Breast self-exam, or regularly examining your breasts on your own, can be an important way to...HER2 (human epidermal growth factor receptor 2) is a gene that can play a role in the development...Stay informed about current research, online events, and more. It's very difficult to get any appointments with the unit as they are very busy, but I will ask.
I didn't get these tablets until after radiotherapy as they are your belt and braces felt it must be all right to have the delay otherwise they wouldn't do it. We’re here to provide physical, financial and emotional support.© Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). Breastcancer.org is a registered 501(c)(3) nonprofit organization dedicated to providing information and community to those touched by this disease.
Do not start, stop, or change the dose of any drug without checking with your doctor. Women who took Femara then tamoxifen or tamoxifen then Femara were more likely to stop taking hormonal therapy early.
If you find the side effects ease within the two weeks they may try you on Anastrozole or even Exemstane. I have been taking Letrozole since I finished chemo in September 2016, my SE were not too bad but they are getting worse. I'm wondering, first, if the abrupt stop of Letrozole will bring on a new set of side effects, and second, what have any of you experienced with the tamoxifen.
Compliance results.
Hi,, i have had a couple of breaks off it for a 2 or 3 week period, which you can do, the drug is accumulative so it stays in your system for a while.. your clicking thumb is normal, some get it some dont, i had it, and its been gone now for some months,, it just takes time for your body to get rid of all the stuff its been given.. joint wise, you need to speak and see your oncologist not your GP,, they will change you onto a brand if you are really suffering, but you will get some joint pain on any of them, but it should be bearable and allow you to function, but you will need to try brands for about a month or so to see if any are better for you.. hope it goes well Sally xxx Overall, 5.1% of the women were not compliant with the hormonal therapy.
I know it's scary but I had an allergic reaction to letrozole and had to stop taking all my medication including my in gales and lanzaporole and then slowly introduced them back but not the letrozole I have now been put on exemestane and yes still have joint pain but if it's to bad I take paracetamol. I had done a bit of research while taking it, I had a year of misery with stiff joints, hot flushes through the roof & feeling sluggish probably because of weight gain.
Research has shown that about 25% of women who are prescribed hormonal therapy to reduce the risk of recurrence after surgery either don’t start taking the medicine or stop taking it early, in many cases because of side effects.
The percentages of women who didn’t complete the prescribed course of therapy by treatment type were:
Side effects caused by hormonal therapy can be very troublesome for many women.
Disease-free survival was defined as how long the women lived without the cancer coming back or a new cancer being diagnosed in the opposite breast. Learn more about Not Taking Hormonal Therapy as Prescribed Leads to More Recurrence Aromatase inhibitors may cause muscle and joint aches and pains.
Tell all of your health care providers that you take letrozole.
Good luck.
Stopped taking Letrozole for 2 weeks advice please very worried
They both do the same job but Anastrozole is the more similar tablet so could well have similar side effects -You could ask about the Exemestane which I think are steroid based ?Thanks for the information, I have put on a lot of weight as well, would the Exemestane which could be steroid based make this worse. Women who stopped taking hormonal therapy early were 35% to 56% more likely to have a recurrence than women who didn’t stop taking the medicine early.
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